ArticleArab journal of urology2021
The effect of paternal age on intracytoplasmic sperm injection outcome in unexplained infertility.
Article in Arab journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Clinical Implications of Paternal Age in Assisted Reproduction: Integrating Sperm Epigenetic Evidence.Journal of clinical medicine · 2026Review
- Association of paternal age with embryological outcomes and β-hCG positivity in women with polycystic ovary syndrome undergoing ICSI: a retrospective cohort study.Frontiers in medicine · 2026Article
- Association of sperm protamine1 and protamine2 transcript content with paternal age: A cross-sectional study.International journal of reproductive biomedicine · 2025Article
- Impact of Male Age and Semen Parameters on Blastocyst Morphology, Beta-HCG Positivity and Pregnancy Viability: A Retrospective Analysis in Frozen Embryo Transfer Cycles.Journal of obstetrics and gynaecology of India · 2025Article
- Livebirth rates are influenced by an interaction between male and female partners' age: analysis of 59 951 fresh IVF/ICSI cycles with and without male infertility.Human reproduction (Oxford, England) · 2024Article
- Reassessing Semen Analysis: Clinical Insights Beyond Sperm Count and Motility.Reproductive medicine and biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective: To examine the effect of paternal age on intracytoplasmic sperm injection (ICSI) outcomes in unexplained infertility. SUBJECTS AND
methods: This retrospective study, done at the Hamad Medical Corporation, Doha, Qatar screened infertile couples who underwent ICSI between 2014 and 2019 for the inclusion and exclusion criteria defining 'unexplained infertility'. Couples recruited were allocated into two groups: Group A (paternal age <35 years) and Group B (paternal age ≥35 years). Baseline characteristics, investigations including semen and advanced sperm function tests and ICSI records were compared for primary outcomes such as fertilisation, cleavage, clinical pregnancy, miscarriage and live birth; and secondary outcomes such as semen parameters and advanced sperm functions (DNA fragmentation index and oxidation reduction potential).
results: We found that final pregnancy outcomes including clinical pregnancy rate (
conclusions: Advanced paternal age affects sperm morphology, fertilisation and embryo cleavage in ICSI but does not appear to affect clinical pregnancy, miscarriage or live-birth rates. ICSI appears to be a valid fertility treatment option in advancing paternal age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.