Evidence map›Paper›PMID 34552662›Full record

ArticleResearch in autism spectrum disorders2019

Injury-related treatments and outcomes in preschool children with autism spectrum disorder: Study to Explore Early Development (SEED).

Carolyn DiGuiseppi, Katherine R Sabourin, Susan E Levy, Gnakub N Soke, Li-Ching Lee, Lisa Wiggins, Laura A Schieve

Abstract read
In one paragraph

Article in Research in autism spectrum disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolyn DiGuiseppiUniversity of Colorado Anschutz Medical Campus, Colorado School of Public Health, Department of Epidemiology, Aurora, CO 80045 United States.
Katherine R SabourinUniversity of Colorado Anschutz Medical Campus, Colorado School of Public Health, Department of Epidemiology, Aurora, CO 80045 United States.
Susan E LevyThe Children's Hospital of Philadelphia at University of Pennsylvania, Philadelphia, PA 19104 United States.
Gnakub N SokeCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30341 United States.
Li-Ching LeeJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD 21205 United States.
Lisa WigginsCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30341 United States.
Laura A SchieveCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30341 United States.

Funding

Intramural CDC HHS CC999999NCBDD CDC HHS U01 DD000498NCBDD CDC HHS U01 DD001210NCBDD CDC HHS U10 DD000180NCBDD CDC HHS U10 DD000181NCBDD CDC HHS U10 DD000182NCBDD CDC HHS U10 DD000183NCBDD CDC HHS U10 DD000184
6 · The paper itself

Abstract

backgroundEvidence about injury management and outcomes in children with autism spectrum disorder (ASD) is limited.

methodCross-sectional analyses included children aged 30-68 months with at least one medically attended injury. Standardized diagnostic instruments determined ASD cases. Parent-reported injury treatments and outcomes were examined in ASD cases (n = 224) versus developmental delays/disorders (DD) (n = 188) and population (POP) (n = 267) controls, adjusting for child and family characteristics using logistic regression.

resultsInjury characteristics were similar between groups. Most children (82.5%) had emergency care (EC) or hospitalization after injury. Nearly half (46.4%) ever received a medication or injection, mostly analgesics (53.4%) and local anesthetics (23.8%), while 9.4% ever received surgery, most often for open wound (47.0%) or fracture (16.7%). ASD group children were less likely than DD group children to receive medication/injection (41.1% vs. 53.2%, adjusted odds ratio [aOR] = 0.60 [0.40, 0.90]); receipt of EC/hospitalization and surgery were comparable. Children with ASD more often had surgery than POP children (14.3% vs. 4.9%, aOR = 2.62 [1.31, 5.25]); receipt of EC/hospitalization and medication/injection were similar. Loss of consciousness was uncommon (ASD = 6.3%, DD = 5.3%, POP = 3.4%), as was long-term or significant behavior change (ASD = 5.4%, DD = 3.2%, POP = 3.2%); differences were not significant.

conclusionsInjured children with ASD received fewer medications/injections than children with non-ASD developmental delays/disorders and more surgical treatments than general population children. Injury management was otherwise similar between groups. Understanding whether these results reflect child or injury characteristics or provider perceptions about behaviors and pain thresholds of children with ASD, and how these may influence care, requires further study.

Indexed as

ASDEmergency careInjuriesInjury outcomesSurgeryTreatment

Identifiers

PMID34552662
PMCPMC8455161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.