ArticleInternational journal of endocrinology2021
Efficacy and Safety of Single-Session Radiofrequency Ablation in Treating Benign Thyroid Nodules: A Short-Term Prospective Cohort Study.
Article in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Safety and efficacy of thermal ablation for cervical metastatic lymph nodes in papillary thyroid carcinoma: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Early volume reduction slope as a novel predictor of long-term outcomes following microwave ablation of benign thyroid nodules: a machine learning-enhanced prediction model.Journal of ultrasound · 2026Article
- Single-session radiofrequency ablation for the treatment of benign cystic thyroid nodules: A prospective study.PloS one · 2026Article
- Ultrasound-Guided Fine-Needle Aspiration Biopsy Of Thyroid Nodules Smaller Than 10 mm in the Maximum Diameter: The Efficacy and Its Correlation with TIRADS Classification.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Radiofrequency ablation for thyroid nodules in Ecuador: a cross-sectional study.Thyroid research · 2024Article
- Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules.Bioengineering (Basel, Switzerland) · 2023Article
- Effect of ultrasound parameters of benign thyroid nodules on radiofrequency ablation efficacy.BMC medical imaging · 2023Article
- Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study.Therapeutics and clinical risk management · 2023Article
- Efficacy and Safety of Radiofrequency Ablation for the Treatment of Autonomously Functioning Thyroid Nodules: A Long-Term Prospective Study.Therapeutics and clinical risk management · 2022Article
- Long-term outcome of microwave ablation for benign thyroid nodules: Over 48-month follow-up study.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aims of this study are to evaluate the safety and efficacy of RFA in the treatment of benign thyroid nodule(s) and to find independent factors related to the volume reduction rate of the nodule(s). MATERIALS AND
methodsThis short-term prospective study from a single medical center was conducted on 93 benign thyroid nodules in 93 patients treated with RFA. Two basic techniques were used: the trans-isthmic approach and moving-shot technique. Clinical and ultrasonography examinations were performed at 1- and 3-month follow-up after the treatment session. Primary outcomes included volume reduction ratio (VRR) at 1-month and 3-month follow-ups; secondary outcomes were therapeutic success rate and complications. Multiple linear regression analysis was used to determine independent factors associated with VRR.
resultsA final sample of 78 patients with 78 nodules, given participant rate 83.8% (including 60 solid nodules, 16 predominantly cystic nodules, and 2 thyroid cysts), was followed up for 3 months. The mean volume reduction ratio was 41.47% and 64.72% after 1-month and 3-month follow-ups, respectively. The therapeutic success rate was 30.8% at 1-month and 84.6% at 3-month follow-ups. Symptom score and cosmetic score improved significantly. There was no change in thyroid function tests. Two minor complications (transient voice change) were found. The multiple linear regression analysis showed that the internal component of the nodules significantly related to the VRR during the 3-month follow-up (
conclusionRFA was demonstrated as a safe and effective option for benign thyroid nodules treatment. It can be used as an alternative treatment with encouraging results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.