Evidence map›Paper›PMID 34552508›Full record

ArticleFrontiers in physiology2021

Remote Ischemic Preconditioning Reduces Marathon-Induced Oxidative Stress and Decreases Liver and Heart Injury Markers in the Serum.

Jan Mieszkowski, Błaz Ej Stankiewicz, Andrzej Kochanowicz, Bartłomiej Niespodziński, Andz Elika Borkowska, Katarzyna Sikorska, Ludmiła Daniłowicz-Szymanowicz, Paulina Brzezińska, Jędrzej Antosiewicz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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  12. From gains to liver pain: when exercise training goes too far.Extracellular vesicles and circulating nucleic acids · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jan MieszkowskiDepartment of Gymnastics and Dance, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Błaz Ej StankiewiczDepartment of Human Biology, Institute of Physical Education, Kazimierz Wielki University, Bydgoszcz, Poland.
Andrzej KochanowiczDepartment of Gymnastics and Dance, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Bartłomiej NiespodzińskiDepartment of Human Biology, Institute of Physical Education, Kazimierz Wielki University, Bydgoszcz, Poland.
Andz Elika BorkowskaDepartment of Bioenergetics and Physiology of Exercise, Faculty of Health Sciences, Medical University of Gdańsk, Gdańsk, Poland.
Katarzyna SikorskaDepartment of Tropical and Parasitic Diseases, Faculty of Health Sciences, Medical University of Gdańsk, Gdańsk, Poland.
Ludmiła Daniłowicz-SzymanowiczDepartment of Cardiology and Electrotherapy, Medical University of Gdańsk, Gdańsk, Poland.
Paulina BrzezińskaDepartment of Gymnastics and Dance, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Jędrzej AntosiewiczDepartment of Bioenergetics and Physiology of Exercise, Faculty of Health Sciences, Medical University of Gdańsk, Gdańsk, Poland.
Gdańsk Medical University · PLGdansk University of Physical Education and Sport · PLKazimierz Wielki University in Bydgoszcz · PLCharles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical studies continue to provide evidence of organ protection by remote ischemic preconditioning (RIPC). However, there is lack of insight into impact of RIPC on exercise-induce changes in human organs' function. We here aimed to elucidate the effects of 10-day RIPC training on marathon-induced changes in the levels of serum markers of oxidative stress, and liver and heart damage. The study involved 18 male amateur runners taking part in a marathon. RIPC training was performed in the course of four cycles, by inflating and deflating a blood pressure cuff at 5-min intervals (RIPC group,

Indexed as

creatinine kinase MBinflammationmalondialdehyderemote ischemic preconditioningskeletal muscle damage

Identifiers

PMID34552508
PMCPMC8450527
OpenAlexW3198773961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.