Evidence map›Paper›PMID 34552277›Full record

ArticleMacromolecules2021

Efficient Exchange in a Bioinspired Dynamic Covalent Polymer Network via a Cyclic Phosphate Triester Intermediate.

Soumabrata Majumdar, Brahim Mezari, Huiyi Zhang, Jeroen van Aart, Rolf A T M van Benthem, Johan P A Heuts, Rint P Sijbesma

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Macromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Soumabrata MajumdarDepartment of Chemical Engineering & Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Brahim MezariDepartment of Chemical Engineering & Chemistry, Laboratory of Inorganic Materials and Catalysis, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Huiyi ZhangDepartment of Chemical Engineering & Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Jeroen van AartDepartment of Chemical Engineering & Chemistry, Laboratory of Physical Chemistry, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Rolf A T M van BenthemDepartment of Chemical Engineering & Chemistry, Laboratory of Physical Chemistry, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Johan P A HeutsDepartment of Chemical Engineering & Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.ORCID https://orcid.org/0000-0002-9505-8242
Rint P SijbesmaDepartment of Chemical Engineering & Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.ORCID https://orcid.org/0000-0002-8975-636X
Eindhoven University of Technology · NLDSM (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bond exchange via neighboring group-assisted reactions in dynamic covalent networks results in efficient mechanical relaxation. In Nature, the high reactivity of RNA toward nucleophilic substitution is largely attributed to the formation of a cyclic phosphate ester intermediate via neighboring group participation. We took inspiration from RNA to develop a dynamic covalent network based on β-hydroxyl-mediated transesterifications of hydroxyethyl phosphate triesters. A simple one-step synthetic strategy provided a network containing phosphate triesters with a pendant hydroxyethyl group.

Identifiers

PMID34552277
PMCPMC8444552
OpenAlexW3195639489

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.