Evidence map›Paper›PMID 34552113›Full record

ArticleScientific reports2021

Ene-reductase transformation of massoia lactone to δ-decalactone in a continuous-flow reactor.

Ewa Szczepańska, Danilo Colombo, Francesca Tentori, Teresa Olejniczak, Elisabetta Brenna, Daniela Monti, Filip Boratyński

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Toward Sustainability: Intensification of Light-Driven Whole Cell Biocatalysis.Chembiochem : a European journal of chemical biology · 2026
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  6. HCommunications chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ewa Szczepańska *Department of Chemistry, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375, Wrocław, Poland. ewa.szczepanska@upwr.edu.pl.
Danilo ColomboDipartimento di Chimica, Materiali ed Ingegneria Chimica "Giulio Natta" Politecnico di Milano, Via Mancinelli 7, 20131, Milan, Italy.
Francesca TentoriDipartimento di Chimica, Materiali ed Ingegneria Chimica "Giulio Natta" Politecnico di Milano, Via Mancinelli 7, 20131, Milan, Italy.
Teresa OlejniczakDepartment of Chemistry, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375, Wrocław, Poland.
Elisabetta BrennaDipartimento di Chimica, Materiali ed Ingegneria Chimica "Giulio Natta" Politecnico di Milano, Via Mancinelli 7, 20131, Milan, Italy.
Daniela MontiIstituto di Scienze e Tecnologie Chimiche "Giulio Natta" (SCITEC)-CNR, Via Mario Bianco 9, 20131, Milan, Italy.
Filip Boratyński *Department of Chemistry, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375, Wrocław, Poland. filip.boratynski@upwr.edu.pl.
Politecnico di Milano · ITWroclaw University of Environmental and Life Sciences · PLIstituto di Scienze e Tecnologie Chimiche "Giulio Natta"

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The demand for natural food flavorings increases every year. Biotransformation has become an attractive approach to obtain natural products. In this work, enantiomerically pure (R)-(+)-δ-decalactone was obtained by reduction of the C=C double bond of natural massoia lactone in a continuous-flow reactor. Of 13 different ene-reductases isolated, purified and tested, OYE3 was found to be the most efficient biocatalyst. The selected biocatalyst, either in the form of purified enzyme, cell lysate, whole cells or immobilized cells, was tested in the batch system as well as in the packed-bed flow bioreactor. The biotransformation performed in batch mode, using Ca

Indexed as

BioreactorsBacillus megateriumCells, ImmobilizedCryptocaryaEscherichia coliLactonesMetabolic Networks and PathwaysOxidoreductasesPlant BarkSilver NitrateFontana-Masson stainLactonesOxidoreductasesSilver Nitrate

Identifiers

PMID34552113
PMCPMC8458379
OpenAlexW3199418000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.