Evidence map›Paper›PMID 34551980›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Shotgun scanning glycomutagenesis: A simple and efficient strategy for constructing and characterizing neoglycoproteins.

Mingji Li, Xiaolu Zheng, Sudhanshu Shanker, Thapakorn Jaroentomeechai, Tyler D Moeller, Sophia W Hulbert, Ilkay Koçer, Josef Byrne, Emily C Cox, Qin Fu and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  12. Ribosome Stalling ofACS synthetic biology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Mingji LiRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853.ORCID 0000-0003-2455-3307
Xiaolu ZhengRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853.
Sudhanshu ShankerDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218.ORCID 0000-0002-6858-4714
Thapakorn JaroentomeechaiRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853.
Tyler D MoellerRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-2912-2621
Sophia W HulbertBiochemistry, Molecular and Cell Biology, Cornell University, Ithaca, NY 14853.
Ilkay KoçerRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853.
Josef ByrneRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853.
Emily C CoxBiomedical and Biological Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
Qin FuCornell Institute of Biotechnology, Cornell University, Ithaca, NY 14853.
Sheng ZhangCornell Institute of Biotechnology, Cornell University, Ithaca, NY 14853.ORCID 0000-0001-8206-1007
Jason W LabonteDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218.
Jeffrey J GrayDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218; jgray@jhu.edu md255@cornell.edu.ORCID 0000-0001-6380-2324
Matthew P DeLisaRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853; jgray@jhu.edu md255@cornell.edu.ORCID 0000-0003-3226-1566
Cornell University · USJohns Hopkins University · US

Funding

Project 3: Physical and Metabolic Constraints of Cancer Cell InvasionU54CA210184 · NCI · CORNELL UNIVERSITY · PI SCHAFFER, CHRIS B · 2016 to 2020
$10.2M
Molecular toolkit for high content resolution of glycomes by expansionmicroscopyR01GM137314 · NIGMS · CORNELL UNIVERSITY · PI ALABI, CHRISTOPHER AKINLEYE, DELISA, MATTHEW P · 2020 to 2023
$1.8M
Technologies to predict and probe glycosyl transferR01GM127578 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GRAY, JEFFREY J · 2018 to 2020
$1.6M
Immuno-Engineering: Integrated Engineering and Immunology TrainingT32EB023860 · NIBIB · CORNELL UNIVERSITY · PI AUGUST, AVERY, PUTNAM, DAVID A · 2018 to 2022
$933k
Acquisition of a Hybrid Quadrupole Time of Flight LC-MS/MS System for the CornellS10OD017992 · OD · CORNELL UNIVERSITY · PI ZHANG, SHENG · 2014 to 2014
$600k
NCI NIH HHS U54 CA210184NIBIB NIH HHS T32 EB023860NIGMS NIH HHS R01 GM127578NIGMS NIH HHS R01 GM137314NIH HHS S10 OD017992
6 · The paper itself

Abstract

As a common protein modification, asparagine-linked (

Indexed as

Protein Processing, Post-TranslationalAmino Acid SequenceAnimalsAsparagineCarrier ProteinsCattleErb-b2 Receptor Tyrosine KinasesEscherichia coli ProteinsGlycoproteinsGlycosylationHumansPolysaccharidesProtein ConformationProtein EngineeringRibonuclease, PancreaticSingle-Chain AntibodiesAsparagineCarrier ProteinsE colicin-binding immunity protein Im7, E coliERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesEscherichia coli ProteinsGlycoproteinsPolysaccharidesRibonuclease, PancreaticSingle-Chain Antibodiesglycoengineeringglycosylationprotein design and engineeringsynthetic biology

Identifiers

PMID34551980
PMCPMC8488656
OpenAlexW3199817912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.