ArticleProceedings of the National Academy of Sciences of the United States of America2021
Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 142 citations in OpenAlex.
- Context matters: coordinated transcriptional regulation and root plasticity under multinutrient conditions.The New phytologist · 2026Article
- Research Advances in Molecular Mechanisms of Xylem Development in Horticultural Plants.Plants (Basel, Switzerland) · 2026Review
- GWAS reveal SUBER GENE1-mediated suberization via type one phosphatases.Nature plants · 2026Article
- The GAPLESS-OsCASP complex mediates Casparian strip formation for proper localization and abundance of endodermal proteins in rice.Science advances · 2026Article
- Article
- Root cell wall plasticity in iron homeostasis: an overlooked frontier in plant nutrition.The New phytologist · 2026Review
- Regulatory Roles of MYB Transcription Factors in Root Barrier Under Abiotic Stress.Plants (Basel, Switzerland) · 2026Review
- Local adjustment of exodermis to nutrient deficiency in crop species.Frontiers in plant science · 2026Article
- Possible regulation ofmicroPublication biology · 2026Article
- Multifaceted roles and regulatory mechanisms of MYB transcription factors in plant development, secondary metabolism, and stress adaptation: current insights and future prospects.GM crops & food · 2025Review
- Clathrin-mediated endocytosis regulates root endodermal suberization via ROS.The New phytologist · 2025Article
- Transcription factors SlMYB41, SlMYB92, and SlWRKY71 regulate gene expression in the tomato exodermis.Journal of experimental botany · 2025Article
- Dual roles of suberin deposition at the endodermal Casparian strip in manganese uptake of rice.Journal of experimental botany · 2025Article
- Coordination of cortex modifications in time, space, and under stress.The New phytologist · 2025Review
- Regulatory Programmes Driving Suberin Plasticity Under Aluminium Stress in Barley Roots.Plant, cell & environment · 2025Article
- ONAC005 enhances salt stress tolerance by promoting suberin deposition in root endodermis.The Plant journal : for cell and molecular biology · 2025Article
- A Transcriptomic Study on the Toxic Effects of Iodide (ICurrent issues in molecular biology · 2025Article
- Article
- Cytosolic and Nucleosolic Calcium-Regulated Long Non-Coding RNAs and Their Target Protein-Coding Genes in Response to Hyperosmolarity and Salt Stresses inInternational journal of molecular sciences · 2025Article
- Closed Systems to Study Plant-Filamentous Fungi Associations: Emphasis on Microscopic Analyses.Bio-protocol · 2025Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Suberin is a hydrophobic biopolymer that can be deposited at the periphery of cells, forming protective barriers against biotic and abiotic stress. In roots, suberin forms lamellae at the periphery of endodermal cells where it plays crucial roles in the control of water and mineral transport. Suberin formation is highly regulated by developmental and environmental cues. However, the mechanisms controlling its spatiotemporal regulation are poorly understood. Here, we show that endodermal suberin is regulated independently by developmental and exogenous signals to fine-tune suberin deposition in roots. We found a set of four MYB transcription factors (MYB41, MYB53, MYB92, and MYB93), each of which is individually regulated by these two signals and is sufficient to promote endodermal suberin. Mutation of these four transcription factors simultaneously through genome editing leads to a dramatic reduction in suberin formation in response to both developmental and environmental signals. Most suberin mutants analyzed at physiological levels are also affected in another endodermal barrier made of lignin (Casparian strips) through a compensatory mechanism. Through the functional analysis of these four MYBs, we generated plants allowing unbiased investigation of endodermal suberin function, without accounting for confounding effects due to Casparian strip defects, and were able to unravel specific roles of suberin in nutrient homeostasis.
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