Evidence map›Paper›PMID 34551677›Full record

ArticleEmerging microbes & infections2021

Mutations in porin LamB contribute to ceftazidime-avibactam resistance in KPC-producing Klebsiella

Yingyi Guo, Ningjing Liu, Zhiwei Lin, Xiaoliang Ba, Chuyue Zhuo, Feifeng Li, Jiong Wang, Yitan Li, Likang Yao, Baomo Liu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

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  11. CombatingFrontiers in cellular and infection microbiology · 2025
    Review
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Yingyi GuoGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Ningjing LiuGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Zhiwei LinLaboratory of Respiratory Disease, People's Hospital of Yangjiang, Guangdong, People's Republic of China.
Xiaoliang BaDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Chuyue ZhuoGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Feifeng LiGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Jiong WangGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Yitan LiLaboratory of Respiratory Disease, People's Hospital of Yangjiang, Guangdong, People's Republic of China.
Likang YaoGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Baomo LiuGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Shunian XiaoGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Ying JiangGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Chao ZhuoGuangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
First Affiliated Hospital of Guangzhou Medical University · CNPeople's Hospital of Yangzhong · CNUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftazidime-avibactam (CAZ-AVI) shows promising activity against carbapenem-resistant

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCeftazidimeDrug CombinationsHumansKlebsiella InfectionsPorinsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCeftazidimeDrug CombinationsPorinsCeftazidime-avibactamexpression level of blaKPCKPCLamBPBP3

Identifiers

PMID34551677
PMCPMC8567916
OpenAlexW3201048662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.