ArticleCirculation research2021
A Novel Mechanism Underlying Inflammatory Smooth Muscle Phenotype in Abdominal Aortic Aneurysm.
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In one paragraph
Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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33citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
What it found
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Comprehensive Integration of Multiple Single-Cell Transcriptomic Data Sets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2024Pooled it
- ADAR1 and ADAR2 Expression in the Thoracic Aortic Wall Correlates with Aneurysm Severity and Dissection Risk: Insights into A-to-I RNA Editing Dysregulation in Marfan Syndrome-Derived vSMCs.International journal of molecular sciences · 2026Article
- Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation.Experimental & molecular medicine · 2026Article
- Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.Applied biochemistry and biotechnology · 2026Article
- Tenascin C promotes the formation of abdominal aortic aneurysm by regulating the homeostasis of vascular smooth muscle cells.Biology direct · 2026Article
- Adenosine-to-Inosine (A-to-I) RNA Editing by ADAR1 to Control RNA Sensing in Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- PET-microplastics trigger endothelial glycocalyx loss via ER stress and ROS unleashing IL-1β-driven SMC switching and early aortic structural impairment.Journal of nanobiotechnology · 2026Article
- Multi-omics integration reveals the link between gut microbiota dysbiosis, host metabolic dysregulation, and aortic inflammation in abdominal aortic aneurysm.BMC microbiology · 2026Article
- Cell-dependent contributions of thrombospondin-1 to the rupture of abdominal aortic aneurysm in mice.Cardiovascular research · 2026Article
- Emerging Mechanisms of Abdominal Aortic Aneurysm.Current atherosclerosis reports · 2026Review
- Heme as a Pro-Inflammatory Stimulus in Abdominal Aortic Aneurysm.Antioxidants (Basel, Switzerland) · 2026Article
- Thymic stromal lymphopoietin promotes abdominal aortic aneurysm formation by regulating macrophage polarization.Frontiers in immunology · 2026Article
- Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of the RNA sensor MDA5 in atherosclerosis.Nature cardiovascular research · 2025Article
- Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Review
- YTH NCells · 2025Article
- Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2.Journal of inflammation research · 2025Article
- Adenosine kinase inhibition protects mice from abdominal aortic aneurysm via epigenetic modulation of VSMC inflammation.Cardiovascular research · 2024Article
- SLC44A2-mediated phenotypic switch of vascular smooth muscle cells contributes to aortic aneurysm.The Journal of clinical investigation · 2024Article
- Article
- SLC44A2 regulates vascular smooth muscle cell phenotypic switching and aortic aneurysm.The Journal of clinical investigation · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Dunpeng CaiDepartments of Surgery (D.C., X.Q., S.-Y.C.), University of Missouri School of Medicine, Columbia.ORCID 0000-0002-0489-6567
Chenming SunDepartment of Physiology & Pharmacology, University of Georgia, Athens (C.S., G.Z., S.-Y.C.).
Gui ZhangDepartment of Physiology & Pharmacology, University of Georgia, Athens (C.S., G.Z., S.-Y.C.).ORCID 0000-0002-1123-7877
Xingyi QueDepartments of Surgery (D.C., X.Q., S.-Y.C.), University of Missouri School of Medicine, Columbia.ORCID 0000-0003-1094-2790
Ken FujiseHarborview Medical Center, Department of Medicine, University of Washington, Seattle (K.F.).ORCID 0000-0002-6763-8055
Neal L WeintraubDepartment of Medicine (N.L.W.).ORCID 0000-0002-5138-3705
Shi-You ChenDepartments of Surgery (D.C., X.Q., S.-Y.C.), University of Missouri School of Medicine, Columbia.ORCID 0000-0002-0297-8649
University of Georgia · USUniversity of Missouri · USAugusta University · USHarborview Medical Center · US
Funding
Fortilin, p53, and atherosclerosisR01HL117247 · NHLBI · UNIVERSITY OF WASHINGTON · PI CHEN, SHIYOU, FUJISE, KEN · 2013 to 2023
$4.7MNovel mechanism of smooth muscle phenotypic modulation and vascular remodelingR01HL119053 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHEN, SHIYOU · 2014 to 2023
$3.8MFortilin, CTNNA3, and the HeartR01HL152723 · NHLBI · UNIVERSITY OF WASHINGTON · PI FUJISE, KEN · 2021 to 2024
$2.7MUSING FORTILIN INHIBITORS TO BLOCK ATHEROSCLEROSISR01HL138992 · NHLBI · UNIVERSITY OF WASHINGTON · PI FUJISE, KEN, SRIVASTAVA, SANJAY · 2017 to 2020
$2.6MMechanisms of myeloperoxidase and Nox4 interactions in abdominal aortic aneurysmR01HL142097 · NHLBI · AUGUSTA UNIVERSITY · PI WEINTRAUB, NEAL L · 2018 to 2021
$2.1MDedicator of cytokinesis 2 in abdominal aortic aneurysmR01HL147313 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHEN, SHIYOU · 2019 to 2022
$2.1MSmad2 in vascular smooth muscle homeostasisR01HL135854 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHEN, SHIYOU · 2017 to 2020
$2.0MNHLBI NIH HHS R01 HL117247NHLBI NIH HHS R01 HL119053NHLBI NIH HHS R01 HL135854NHLBI NIH HHS R01 HL138992NHLBI NIH HHS R01 HL142097NHLBI NIH HHS R01 HL147313NHLBI NIH HHS R01 HL152723
Abstract
[Figure: see text].
Indexed as
Adenosine DeaminaseAnimalsAortic Aneurysm, AbdominalApolipoproteins ECells, CulturedHumansMaleMatrix Metalloproteinase 2Matrix Metalloproteinase 9MiceMice, Inbred C57BLMuscle, Smooth, VascularADAR1 protein, mouseAdenosine DeaminaseApoe protein, mouseApolipoproteins EMatrix Metalloproteinase 2Matrix Metalloproteinase 9Mmp2 protein, mouseMmp9 protein, mouseangiotensin IIaortic aneurysm, abdominalinterleukinmatrix metalloproteinasephenotype
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.