Evidence map›Paper›PMID 34551174›Full record

ArticleInternational journal of clinical practice2021

Correlation between chest CT severity score and laboratory indicators in patients with Coronavirus disease 2019 (COVID-19).

Qunying Lin, Liangning Wu, Weihua Lin, Linjian Zhu, Yuxiong Hu, Guosheng Lin, Juan Lin, Haijian Tu

Abstract read
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qunying LinPulmonary and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Liangning WuPulmonary and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Weihua LinPulmonary and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Linjian ZhuTuberculosis Ward, Affiliated Hospital of Putian University, Putian, China.
Yuxiong HuPulmonary and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Guosheng LinPulmonary and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Juan LinPulmonary and Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Haijian TuClinical Laboratory, Affiliated Hospital of Putian University, Putian, China.

Funding

Fujian Natural Science Foundation Project 2018J01196Putian Science and Technology Foundation Project 2019SZP02
6 · The paper itself

Abstract

objectiveThe association between computed tomography (CT) and clinical severity of COVID-19 has been demonstrated. However, there are few studies on CT and laboratory indicators in patients in COVID-19. Our aim was to explore the correlation between chest CT images and laboratory indicators of patients with COVID-19 pneumonia.

methodsThis was a retrospective study of patients with COVID-19 diagnosed and treated at the Affiliated Hospital of Putian University from 24 January 2020 to 6 March 2020. The correlation test between first chest CT score and blood cell analysis, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), blood biochemistry and T lymphocyte subsets (T-Ls) was investigated.

resultsAmong the 56 patients, there were 36 (64.3%) males and 20 (35.7%) females. The mean age of the patients was 46.54 ± 15.82 (range, 15-86) years. The CT score in the moderate group was higher than in the mild group (5.06 ± 0.77 vs 1.87 ± 0.88, P < .05), and higher in the severe group than in the moderate and mild groups (10.71 ± 4.21, P < .05). In addition, the ESR was significantly higher in the severe group than mild group (32.00 (26.04, 58.24) vs 11.00 (7.84, 24.70) mm/h, P < .05). The CD3, CD4, CD8 and CD4/CD8 cells were not different (all P > .05). The CT scores of all patients correlated positively with CRP, LDH and ESR (all P < .01).

conclusionThe chest CT characteristics of patients with COVID-19 correlated positively with CRP, ESR and LDH, which may use one of the indicators for the assessment of disease severity.

Indexed as

COVID-19AdolescentAdultAgedAged, 80 and overFemaleHumansLaboratoriesMaleMiddle AgedRetrospective StudiesSARS-CoV-2Tomography, X-Ray ComputedYoung Adult

Identifiers

PMID34551174
PMCPMC8646716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.