Trial reportClinical oral implants research2021
Vertical and horizontal ridge augmentation using customized CAD/CAM titanium mesh with versus without resorbable membranes. A randomized clinical trial.
Trial report in Clinical oral implants research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Efficacy of engineered scaffolds for horizontal and vertical ridge augmentation: A systematic review and meta-analysis.Journal of periodontology · 2026Pooled it
- Clinical Outcomes of Titanium Mesh for Alveolar Bone Augmentation: An Umbrella Review.Clinical and experimental dental research · 2025Pooled it
- Effect of Different Membranes on Vertical Bone Regeneration: A Systematic Review and Network Meta-Analysis.BioMed research international · 2022Pooled it
- Operative Times, Costs and Patient-Related Outcome Measures in Vertical Ridge Augmentation With Customised Reinforced PTFE Mesh Versus CAD/CAM Titanium Mesh: Secondary Analysis of a Randomised Clinical Trial.Journal of clinical periodontology · 2025Trial
- Impact of Collagen Membrane in Vertical Ridge Augmentation Using Ti-Reinforced PTFE Mesh: A Randomised Controlled Trial.Journal of clinical periodontology · 2025Trial
- Complication, vertical bone gain, volumetric changes after vertical ridge augmentation using customized reinforced PTFE mesh or Ti-mesh. A non-inferiority randomized clinical trial.Clinical oral implants research · 2024Trial
- A 3D micro-CT assessment of composition and structure of bone tissue after vertical and horizontal alveolar ridge augmentation using CAD/CAM-customized titanium mesh.Clinical oral implants research · 2024Trial
- Vertical and horizontal ridge augmentation using customized CAD/CAM titanium mesh with versus without resorbable membranes. A randomized clinical trial.Clinical oral implants research · 2021Trial
- Modified split bone block technique for reconstruction of the atrophic edentulous maxilla: a retrospective clinical study.International journal of implant dentistry · 2026Article
- Defect-Adapted Guided Bone Regeneration of the Atrophic Edentulous Maxilla Using a PRGF-Enriched Autogenous Bone/ABBM Composite: A Prospective One-Year Case Series.Materials (Basel, Switzerland) · 2026Article
- 3D-driven alveolar ridge augmentation based on reverse planning: a retrospective case series study.BMC oral health · 2026Article
- Effect of pseudo-periosteum on hard and soft tissue regeneration following lateral bone augmentation using a titanium mesh: an experimentalJournal of periodontal & implant science · 2026Article
- Tenting screw technique for guided bone regeneration: a systematic review and meta-analysis protocol.BMJ open · 2026Article
- Clinical and Radiographic Outcomes of Customized Titanium Mesh vs. Screw Tent-Pole Grafting: A Retrospective Study.Clinical implant dentistry and related research · 2026Article
- Effect of Cortical Block Allograft Tenting Pins for Horizontal Bone Augmentation: A Case Series.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- Guided transpositional bone blocks in esthetic zone: Surgical technique and case report.Clinical advances in periodontics · 2026Article
- Digitally Guided Augmentation With an Autogenous Bone Cylinder-Digital CarroTrack Technique: A Case Report.Case reports in dentistry · 2026Article
- Article
- Influence of SLM-, SLS-, and DMLS-Manufactured Titanium Meshes on Bone Gain Parameters and Complications: A Systematic Review.Dentistry journal · 2025Review
- Effect of different titanium mesh thicknesses on mechanical strength and bone stress: a finite element study.BMC oral health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim was to evaluate the role of resorbable membranes applied over customized titanium meshes related to soft tissue healing and bone regeneration after vertical/horizontal bone augmentation. MATERIALS AND
methodsThirty patients with partial edentulism of the maxilla/mandible, with vertical/horizontal reabsorption of the alveolar bone, and needing implant-supported restorations, were randomly divided into two groups: Group A was treated using only custom-made meshes (Mesh-) and Group B using custom-made meshes with cross-linked collagen membranes (Mesh+). Data collection included surgical/technical and healing complications, "pseudo-periosteum" thickness, bone density, planned bone volume (PBV), regenerated bone volume (RBV), regeneration rate (RR), vertical bone gain (VBG), and implant survival in regenerated areas. Statistical analysis was performed between the two study groups using a significance level of α = .05.
resultsRegarding the healing complications, the noninferiority analysis proved to be inconclusive, despite the better results of group Mesh+ (13%) compared to group Mesh- (33%): estimated value -1.13 CI-95% from -0.44 to 0.17. Superiority approach confirmed the absence of significant differences (p = .39). RBV was 803.27 mm
conclusionThe results showed that customized meshes alone do not appear to be inferior to customized meshes covered by cross-linked collagen membranes in terms of healing complication rates and regeneration rates, although superior results were observed in group Mesh+compared to group Mesh- for all variables.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.