Evidence map›Paper›PMID 34550749›Full record

ArticleJCO oncology practice2021

Socioeconomic and Racial Determinants of Brachytherapy Utilization for Cervical Cancer: Concerns for Widening Disparities.

David Boyce-Fappiano, Kevin A Nguyen, Olsi Gjyshi, Gohar Manzar, Chike O Abana, Ann H Klopp, Mitchell Kamrava, Peter F Orio, Nikhil G Thaker, Firas Mourtada and 2 more

Open access · hybridAbstract read
In one paragraph

Article in JCO oncology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  4. Review
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  9. Disparities in gynecologic cancer incidence, treatment, and survival: a narrative review of outcomes among black and white women in the United States.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2022
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

David Boyce-FappianoThe University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-6044-758X
Kevin A NguyenDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA.
Olsi GjyshiThe University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-2677-3058
Gohar ManzarThe University of Texas MD Anderson Cancer Center, Houston, TX.
Chike O AbanaThe University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0003-0209-8470
Ann H KloppThe University of Texas MD Anderson Cancer Center, Houston, TX.
Mitchell KamravaCedars-Sinai Medical Center, Los Angeles, CA.
Peter F OrioDana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, MA.
Nikhil G ThakerArizona Oncology, Tucson, AZ.ORCID 0000-0003-3608-0025
Firas MourtadaChristiana Care Health System, Newark, DE.
Puja VenkatDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA.
Albert J ChangDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA.
The University of Texas MD Anderson Cancer Center · USUniversity of California, Los Angeles · USArizona Oncology · USBrigham and Women's Hospital · USCedars-Sinai Medical Center · USChristiana Care Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCervical cancer (CC) disproportionately affects minorities who have higher incidence and mortality rates. Standard of care for locally advanced CC involves a multimodality approach including brachytherapy (BT), which independently improves oncologic outcomes. Here, we examine the impact of insurance status and race on BT utilization with the SEER database. MATERIALS AND

methodsIn total, 7,266 patients with stage I-IV CC diagnosed from 2007 to 2015 were included. BT utilization, overall survival (OS), and disease-specific survival (DSS) were compared.

resultsOverall, 3,832 (52.7%) received combined external beam radiation therapy (EBRT) + BT, whereas 3,434 (47.3%) received EBRT alone. On multivariate logistic regression analysis, increasing age (OR, 0.98; 95% CI, 0.98 to 0.99;

conclusionThis work demonstrates notable inequities in BT utilization for CC that particularly affects patients of lower insurance status and Black race, which translates into inferior oncologic outcomes. Importantly, the use of BT was able to overcome racial survival differences, thus highlighting its essential value.

Indexed as

BrachytherapyUterine Cervical NeoplasmsFemaleHumansRetrospective StudiesSocioeconomic FactorsUnited States

Identifiers

PMID34550749
PMCPMC8678033
OpenAlexW3200090818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.