Evidence map›Paper›PMID 34550728›Full record

ArticleScience translational medicine2021

MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation.

Nicolette Driscoll, Brian Erickson, Brendan B Murphy, Andrew G Richardson, Gregory Robbins, Nicholas V Apollo, Georgios Mentzelopoulos, Tyler Mathis, Kanit Hantanasirisakul, Puneet Bagga and 11 more

Abstract read
In one paragraph

Article in Science translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Trial
  2. Two-Dimensional MXenes for a Sustainable Future.Journal of the American Chemical Society · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Size Scaling of the Electrochemical Performance of TiSmall (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Size Scaling of the Electrochemical Performance of TibioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Nicolette DriscollDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-8364-460X
Brian EricksonDepartment of Psychology, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0003-1379-3372
Brendan B MurphyDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-3021-6286
Andrew G RichardsonCenter for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-4752-3867
Gregory RobbinsDepartment of Physical Medicine and Rehabilitation, University of Pennsylvania, PA 19104, USA.ORCID 0000-0002-1963-2310
Nicholas V ApolloDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
Georgios MentzelopoulosDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
Tyler MathisDepartment of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.
Kanit HantanasirisakulDepartment of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0002-4890-1444
Puneet BaggaDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-2264-2341
Sarah E GullbrandTranslational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA.ORCID 0000-0001-7806-6606
Matthew SergisonCenter for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.ORCID 0000-0001-6823-7870
Ravinder ReddyDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-4580-2392
John A WolfCenter for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.ORCID 0000-0002-6950-2303
H Isaac ChenCenter for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.ORCID 0000-0002-7431-6046
Timothy H LucasCenter for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Timothy R DillinghamDepartment of Physical Medicine and Rehabilitation, University of Pennsylvania, PA 19104, USA.
Kathryn A DavisCenter for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-7020-6480
Yury GogotsiDepartment of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0001-9423-4032
John D MedagliaDepartment of Psychology, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0002-8372-0139
Flavia VitaleDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-8644-550X

Funding

Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A · 2012 to 2019
$11.3M
Interdisciplinary Engineering Career Development Center in Movement and Rehabilitation SciencesK12HD073945 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, REINKENSMEYER, DAVID JAY · 2012 to 2021
$7.9M
Ghost in the Machine: Melding Brain, Computer and BehaviorDP1NS122038 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI LITT, BRIAN · 2020 to 2024
$5.7M
Training Program in Neuroengineering and MedicineT32NS091006 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brian Litt · 2015 to 2026
$4.1M
Validating MXene Electrodes for Next-Generation ElectroencephalographyR01NS121219 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI MEDAGLIA, JOHN, VITALE, FLAVIA · 2021 to 2025
$2.3M
Dynamic Network Neuroscience and Control Theory: Toward Interventions for Cognitive Control DysfunctionDP5OD021352 · OD · UNIVERSITY OF PENNSYLVANIA · PI MEDAGLIA, JOHN · 2015 to 2019
$2.0M
The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc DegenerationIK2RX003118 · VA · PHILADELPHIA VA MEDICAL CENTER · PI GULLBRAND, SARAH E · 2020 to 2024
–
NIBIB NIH HHS P41 EB015893NICHD NIH HHS K12 HD073945NIH HHS DP5 OD021352NINDS NIH HHS DP1 NS122038NINDS NIH HHS R01 NS121219NINDS NIH HHS T32 NS091006RRD VA IK2 RX003118
6 · The paper itself

Abstract

Soft bioelectronic interfaces for mapping and modulating excitable networks at high resolution and at large scale can enable paradigm-shifting diagnostics, monitoring, and treatment strategies. Yet, current technologies largely rely on materials and fabrication schemes that are expensive, do not scale, and critically limit the maximum attainable resolution and coverage. Solution processing is a cost-effective manufacturing alternative, but biocompatible conductive inks matching the performance of conventional metals are lacking. Here, we introduce MXtrodes, a class of soft, high-resolution, large-scale bioelectronic interfaces enabled by Ti

Indexed as

Electrophysiological PhenomenaElectrophysiology

Identifiers

PMID34550728
PMCPMC8722432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.