ArticleMethods in molecular biology (Clifton, N.J.)2022
Living Systematic Reviews.
Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Keeping Pace with Wearables: A Living Umbrella Review of Systematic Reviews Evaluating the Accuracy of Consumer Wearable Technologies in Health Measurement.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Peripheral immune function and Alzheimer's disease: a living systematic review and critical appraisal.Molecular psychiatry · 2024Pooled it
- The Impact of Exercise Prescription Variables on Intervention Outcomes in Musculoskeletal Pain: An Umbrella Review of Systematic Reviews.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Identifying patterns of reported findings on long-term cardiac complications of COVID-19: a systematic review and meta-analysis.BMC medicine · 2023Pooled it
- Past, present and future of living systematic review: a bibliometrics analysis.BMJ global health · 2022Pooled it
- A living systematic review, meta-analysis, and open data resource of trials of MDMA-assisted therapy for PTSD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Conducting evidence synthesis and developing evidence-based advice in public health and beyond: A scoping review and map of methods guidance.Research synthesis methods · 2026Article
- Where did I leave my systematic review protocol, and what should it contain regarding Trial Sequential Analysis?BMC medical research methodology · 2026Article
- Mining the neuroimaging literature.eLife · 2025Article
- Pharmacological interventions in IgA nephropathy: protocol for a living systematic review and network meta-analysis.BMJ open · 2025Article
- Development and evaluation of prompts for a large language model to screen titles and abstracts in a living systematic review.BMJ mental health · 2025Article
- How the National Library of Medicine should evolve in an era of artificial intelligence.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- Collaborative large language models for automated data extraction in living systematic reviews.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- Article
- Cost-effectiveness of falls prevention strategies for older adults: protocol for a living systematic review.BMJ open · 2024Article
- Collaborative Large Language Models for Automated Data Extraction in Living Systematic Reviews.medRxiv : the preprint server for health sciences · 2024Article
- Research to Confront Climate Change Complexity: Intersectionality, Integration, and Innovative Governance.Earth's future · 2024Article
- Optimizing process and methods for a living systematic review: 30 search updates and three review updates later.Journal of clinical epidemiology · 2024Article
- Health systems resilience in fragile and conflict-affected settings: a systematic scoping review.Conflict and health · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systematic reviews are difficult to keep up to date, but failure to do so leads to poor review currency and accuracy. "Living systematic review" (LSR) is an approach that aims to continually update a review, incorporating relevant new evidence as it becomes available. LSRs may be particularly important in fields where research evidence is emerging rapidly, current evidence is uncertain, and new research may change policy or practice decisions.This chapter describes the concept and processes of living systematic reviews. It describes the general principles of LSRs, when they might be of particular value, and how their procedures differ from conventional systematic reviews. The chapter focuses particularly on two methods of sequential meta-analysis that may be particularly useful for LSRs: Trial Sequential Analysis and Sequential Meta-Analysis, which both control for Type I error, Type II error (failing to detect a genuine effect) and take account of heterogeneity.
Indexed as
Identifiers
34550587What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.