Evidence map›Paper›PMID 34550569›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

The Role of Oxytocin in Social Circuits and Social Behavior in Dementia.

Olivier Piguet, Rebekah M Ahmed, Fiona Kumfor

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Olivier PiguetSchool of Psychology and Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia. olivier.piguet@sydney.edu.au.
Rebekah M AhmedCentral Sydney Medical School and Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia.
Fiona KumforSchool of Psychology and Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia.
University of Sydney · AURoyal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Administration of intranasal oxytocin has been found to improve social cognition in a number of brain conditions, including autism spectrum disorder and schizophrenia. Whether this approach is relevant in dementias is currently unknown, particularly in frontotemporal dementia, a younger-onset dementia characterized clinically by marked changes in social cognition and behavior and focal atrophy of the frontal and temporal lobes. This chapter provides an overview of the deficits in social cognition in frontotemporal dementia and reviews the emerging evidence of intranasal oxytocin administration as a potential treatment option for these deficits. Future research directions will also be discussed.

Indexed as

Social BehaviorAutism Spectrum DisorderFrontotemporal DementiaHumansNeuropsychological TestsOxytocinOxytocinAlzheimer’s diseaseEmotion processionEmpathyFrontotemporal dementiaHypothalamusNeuroimagingProgressive nonfluent aphasiaSemantic dementiaSocial cognition

Identifiers

PMID34550569
OpenAlexW3201217637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.