Evidence map›Paper›PMID 34550227›Full record

ArticleArquivos brasileiros de cardiologia2021

Atrial Fibrillation Diagnosis using ECG Records and Self-Report in the Community: Cross-Sectional Analysis from ELSA-Brasil.

Itamar S Santos, Paulo A Lotufo, Luisa Brant, Marcelo M Pinto Filho, Alexandre da Costa Pereira, Sandhi Maria Barreto, Antonio L Ribeiro, G Neil Thomas, Gregory Y H Lip, Isabela M Bensenor

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Brazilian Atrial Fibrillation Guidelines - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  2. Atrial fibrillation in the Americas.Lancet regional health. Americas · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Cardiovascular Statistics - Brazil 2023.Arquivos brasileiros de cardiologia · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Itamar S SantosHospital Universitário da Universidade de São Paulo, Centro de Pesquisa Clínica e Epidemiológica, São Paulo, SP - Brasil.ORCID 0000-0003-3212-8466
Paulo A LotufoHospital Universitário da Universidade de São Paulo, Centro de Pesquisa Clínica e Epidemiológica, São Paulo, SP - Brasil.
Luisa BrantFaculdade de Medicina da Universidade Federal de Minas Gerais, Departamento de Clínica Médica, Belo Horizonte, MG - Brasil.ORCID 0000-0002-7317-1367
Marcelo M Pinto FilhoFaculdade de Medicina da Universidade Federal de Minas Gerais - Programa de Pós-Graduação em Infectologia e Medicina Tropical, Belo Horizonte, MG - Brasil.ORCID 0000-0002-6646-1163
Alexandre da Costa PereiraInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - Laboratório de Genética e Cardiologia Molecular, São Paulo, SP - Brasil.
Sandhi Maria BarretoUniversidade Federal de Minas Gerais, Belo Horizonte, MG - Brasil.
Antonio L RibeiroUniversidade Federal de Minas Gerais - Centro de Telessaúde - Hospital das Clínicas - UFMG, Belo Horizonte, MG - Brasil.ORCID 0000-0002-2740-0042
G Neil ThomasUniversity of Birmingham College of Medical and Dental Sciences - Institute of Applied Health Research, Birmingham - Reino Unido da Grã-Bretanha.
Gregory Y H LipUniversity of Liverpool - Liverpool Centre for Cardiovascular Science, Liverpool, Merseyside - Reino Unido da Grã-Bretanha.
Isabela M BensenorHospital Universitário da Universidade de São Paulo, Centro de Pesquisa Clínica e Epidemiológica, São Paulo, SP - Brasil.
Hospital Universitário da Universidade de São Paulo · BRUniversidade Federal de Minas Gerais · BRUniversity of Birmingham · GBHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRHospital das Clínicas da Universidade Federal de Minas Gerais · BRUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation or flutter (AFF) is the most common sustained cardiac arrhythmia. Limited data can be found on AFF epidemiology in South America.

objectiveThe present study sought to describe the clinical epidemiology of AFF and the use of stroke prevention medication in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline assessment.

methodsThis study analyzed data from 13,260 ELSA-Brasil participants. AFF was defined according to ECG recording or by self-report. Logistic regression models were built to analyze factors associated with AFF. This study also analyzed if age and sex were associated with anticoagulant use for stroke prevention. Significance level was set at 5%.

resultsMedian age was 51 years and 7,213 (54.4%) participants were women. AFF was present in 333 (2.5%) participants. Increasing age (odds ratio [OR]:1.05; 95% confidence interval [95%CI]: 1.04-1.07), hypertension (OR:1.44; 95%CI: 1.14-1.81), coronary heart disease (OR: 5.11; 95%CI: 3.85-6.79), heart failure (OR:7.37; 95%CI: 5.00-10.87), and rheumatic fever (OR:3.38; 95%CI: 2.28-5.02) were associated with AFF. From 185 participants with AFF and a CHA2DS2-VASc score ≥2, only 20 (10.8%) used anticoagulants (50.0% among those with AFF in the baseline ECG). Stroke prevention in this group was associated with a higher age (1.8% vs 17.7% in those aged ≤ 54 and ≥ 65 years, respectively; p=0.013). A trend towards a reduced anticoagulant use was observed in women (7.1% vs. 16.4% in women and men, respectively; p=0.055).

conclusionsAt the ELSA-Brasil baseline, 2.5% of the participants had AFF. The lack of stroke prevention was common, which is an especially challenging point for healthcare in this setting.

Indexed as

Atrial FibrillationStrokeAdultAgedAnticoagulantsCross-Sectional StudiesElectrocardiographyFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk AssessmentRisk FactorsSelf ReportAnticoagulants

Identifiers

PMID34550227
PMCPMC8462958
OpenAlexW3196934077

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.