Observational studyArquivos brasileiros de oftalmologia2021
Corneal structure and endothelial morphological changes after uneventful phacoemulsification in type 2 diabetic and nondiabetic patients.
Observational study in Arquivos brasileiros de oftalmologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients.BMC ophthalmology · 2023Pooled it
- Comparison of endothelial cell loss in diabetic patients after conventional phacoemulsification and femtosecond laser-assisted cataract surgery.BMC ophthalmology · 2023Trial
- Active-fluidics versus gravity-fluidics system in phacoemulsification for type 2 diabetes mellitus without diabetic retinopathy: a retrospective observational study.BMC ophthalmology · 2026Observational
- Visual Outcomes and Complication Profiles of Phacoemulsification in Diabetic Versus Non-diabetic Patients.Cureus · 2026Review
- Corneal Endothelial Cell Loss Following Cataract Surgery in Patients with Type 2 Diabetes Mellitus: A Comprehensive Review.Biomedicines · 2025Review
- Impact of Well-Controlled Type 2 Diabetes on Corneal Endothelium Following Cataract Surgery: A Prospective Longitudinal Analysis.Journal of clinical medicine · 2025Article
- ITrace study on the Effects of Phacoemulsification with 90° Transparent Corneal Incision on Corneal Astigmatism and Visual Acuity in Patients Undergoing Cataract Surgery.Pakistan journal of medical sciences · 2024Article
- Review
- Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients.Diagnostics (Basel, Switzerland) · 2023Article
- Comparative assessment of the corneal endothelium following phacoemulsification surgery in patients with type II diabetes and nondiabetes.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Comparison of corneal endothelial cell morphology in type-2 diabetes and nondiabetics.Oman journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to compare corneal structure and endothelial morphological changes after uneventful phacoemulsification cataract surgery between type 2 diabetic and nondiabetic patients and to determine the preoperative and intraoperative factors that may predict greater endothelial cell density loss.
methodsForty-five diabetic pa-tients (45 eyes) and 43 controls (43 eyes) with age-related cataract were enrolled in this prospective observational study. Corneal (thickness and volume) and anterior segment parameters were measured by Scheimpflug tomography; endothelial cell density and morphology (coefficient of variation of cell size, hexagonal cells) were recorded using noncontact specular microscopy. Patients were evaluated preoperatively and at one and six months after surgery. Univariate and multivariate linear regression analyses were performed to evaluate the relationship between demographic, clinical, ocular, and intraoperative parameters and postoperative endothelial cell density changes at six months.
resultsSignificant postoperative endothelial cell loss occurred one month after surgery in both groups (p<0.001), which remained stable until month 6; there were no differences between patients with and without diabetes mellitus at any time point. The mean postoperative central corneal thickness at one and six months did not change significantly from the mean preoperative value in either group (p>0.05). Multivariate linear regression analysis showed that older age (p=0.042) and higher cataract grades (p=0.001) were significantly associated with greater endothelial cell density reduction at six-month follow-up.
conclusionThis study showed that older age and denser cataracts might be associated with greater endothelial cell density reduction after cataract surgery. Other factors, such as diabetes mellitus and preoperative anterior segment parameters, did not influence postoperative changes in endothelial cell density.
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