ArticleClinics (Sao Paulo, Brazil)2021
Spontaneous pneumomediastinum incidence and clinical features in non-intubated patients with COVID-19.
Article in Clinics (Sao Paulo, Brazil), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Clinical characteristics of 40 patients with spontaneous pneumomediastinum: a retrospective study and literature review.Journal of cardiothoracic surgery · 2026Review
- Spontaneous Pneumomediastinum in COVID-19 and Myasthenic-like Symptom Complications in Two Relatives: A Coincidence or Spike Toxicity with Thymic Response in Predisposed Individuals? Two Clinical Cases with a Comprehensive Literature Review.Journal of clinical medicine · 2025Article
- Computed tomography imaging-guided parasternal approach drainage for children with tension pneumomediastinum: a case series.BMC pediatrics · 2023Article
- Severe SARS-CoV-2 Pneumonia and Pneumomediastinum/Pneumothorax: A Prospective Observational Study in an Intermediate Respiratory Care Unit.Journal of intensive care medicine · 2023Observational
- Pneumomediastinum in COVID-19 disease: Clinical review with emphasis on emergency management.Journal of the American College of Emergency Physicians open · 2023Review
- Case report: Severe pneumonia and pneumomediastinum in a previously robust adolescent caused by Omicron BA.5.2.Frontiers in medicine · 2023Article
- Pneumomediastinum and Pneumopericardium as Uncommon Complications of COVID-19 Infection: A Review Article.Cureus · 2022Review
- A Case Series of Secondary Spontaneous Pneumomediastinum and Pneumothorax in Severe COVID-19 Pneumonia.Cureus · 2022Article
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5 authors.
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Abstract
objectivesTo evaluate the presentation characteristics and disease course of seven patients with COVID-19 who spontaneously developed pneumomediastinum without a history of mechanical ventilation.
methodsA total of seven non-intubated patients with COVID-19, of age ranging from 18-67 years, who developed spontaneous pneumomediastinum between 01 April and 01 October 2020 were included in the study. Patients' demographic data, clinical variables, and laboratory values were examined. Spontaneous pneumomediastinum was evaluated using posteroanterior chest radiography and thorax computed tomography.
resultsDuring the research period, 38,492 patients reported to the emergency department of our hospital with COVID-19 symptoms. Of these, spontaneous pneumomediastinum was detected in seven patients who had no previous history of intubation. Chronic obstructive pulmonary disease (2/7) and asthma bronchiale (2/7) were determined as the most common causes of comorbidity.
conclusionsIn our study, the frequency of spontaneous pneumomediastinum developing without pneumothorax was found to be high in non-intubated patients. Whether this is related to the nature of the disease or it is a result of the increase in cases diagnosed incidentally owing to the increasing use of low-dose computed tomography should be explored in further studies.
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