Evidence map›Paper›PMID 34550036›Full record

ArticleJournal of intensive care medicine2022

Predictive Value of Eosinophil Count on COVID-19 Disease Progression and Outcomes, a Retrospective Study of Leishenshan Hospital in Wuhan, China.

Wei Xuan, Xuliang Jiang, Lili Huang, Shuting Pan, Caiyang Chen, Xiao Zhang, Hui Zhu, Song Zhang, Weifeng Yu, Zhiyong Peng and 1 more

Abstract read
In one paragraph

Article in Journal of intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Immune Response Dynamics and Biomarkers in COVID-19 Patients.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wei XuanRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Xuliang JiangRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Lili HuangRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Shuting PanClinical Center for Investigation, Renji Hospital, Shanghai Jiaotong University, Shanghai, China.
Caiyang ChenRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Xiao ZhangRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Hui ZhuRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Song ZhangRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Weifeng YuRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.
Zhiyong PengZhongnan Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0002-3873-9607
Diansan SuRenji Hospital, 71140Shanghai Jiaotong University, Shanghai, China.ORCID https://orcid.org/0000-0001-9755-1025

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential protective role of eosinophils in the COVID-19 pandemic has aroused great interest, given their potential virus clearance function and the infection resistance of asthma patients to this coronavirus. However, it is unknown whether eosinophil counts could serve as a predictor of the severity of COVID-19.

methodsA total of 1004 patients with confirmed COVID-19 who were admitted to Leishenshan Hospital in Wuhan, China, were enrolled in this study, including 905 patients in the general ward and 99 patients in the intensive care unit (ICU). We reviewed their medical data to analyze the association between eosinophils and ICU admission and death.

resultsOf our 1004 patients with COVID-19, low eosinophil counts/ratios were observed in severe cases. After adjusting for confounders that could have affected the outcome, we found that eosinophil counts might not be a predictor of ICU admission. In 99 ICU patients, 58 of whom survived and 41 of whom died, low eosinophil level was an indicator of death in severe COVID-19 patients with a cutoff value of 0.04 × 10

conclusionOur research revealed that a low eosinophil level is a predictor of death in ICU patients rather than a cause of ICU admission.

Indexed as

COVID-19Disease ProgressionEosinophilsHospitalsHumansIntensive Care UnitsPandemicsRetrospective StudiesSARS-CoV-2asthmacoronavirusCOVID-19eosinophilleukocyte

Identifiers

PMID34550036
PMCPMC8986993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.