Evidence map›Paper›PMID 34550006›Full record

ArticlemSphere2021

The Vancomycin Resistance-Associated Regulatory System VraSR Modulates Biofilm Formation of Staphylococcus epidermidis in an

Youcong Wu, Yuanyuan Meng, Lian Qian, Baixing Ding, Haiyan Han, Hongling Chen, Li Bai, Di Qu, Yang Wu

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Combatting Antibiotic-ResistantJournal of chemical information and modeling · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Effect of Antibiotic Exposure onInternational journal of molecular sciences · 2023
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Youcong WuDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali Universitygrid.440682.c, Dali, Yunnan Province, China.
Yuanyuan MengDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali Universitygrid.440682.c, Dali, Yunnan Province, China.
Lian QianDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali Universitygrid.440682.c, Dali, Yunnan Province, China.
Baixing DingKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan Universitygrid.8547.e, Shanghai, China.
Haiyan HanKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan Universitygrid.8547.e, Shanghai, China.
Hongling ChenDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali Universitygrid.440682.c, Dali, Yunnan Province, China.
Li BaiDepartment of Medical Microbiology and Immunology, School of Basic Medical Sciences, Dali Universitygrid.440682.c, Dali, Yunnan Province, China.
Di QuKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan Universitygrid.8547.e, Shanghai, China.
Yang WuKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan Universitygrid.8547.e, Shanghai, China.
Dali University · CNShanghai Medical College of Fudan University · CNSecond Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The two-component system VraSR responds to the cell wall-active antibiotic stress in Staphylococcus epidermidis. To study its regulatory function in biofilm formation, a

Indexed as

BiofilmsGene Expression ProfilingOperonVancomycin ResistanceAnimalsBacterial ProteinsFemaleGene DeletionMicrobial Sensitivity TestsPolysaccharides, BacterialRabbitsReal-Time Polymerase Chain ReactionStaphylococcus epidermidisBacterial Proteinspolysaccharide intercellular adhesinPolysaccharides, Bacterialbiofilm formationcell deathStaphylococcus epidermidistwo-component regulatory systemVraSR

Identifiers

PMID34550006
PMCPMC8550092
OpenAlexW3200515515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.