Evidence map›Paper›PMID 34549982›Full record

ArticleJournal of virology2021

Human Herpesvirus 6A Tegument Protein U14 Induces NF-κB Signaling by Interacting with p65.

Salma Aktar, Jun Arii, Lidya Handayani Tjan, Mitsuhiro Nishimura, Yasuko Mori

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Salma AktarDivision of Clinical Virology, Center for Infectious Diseases, Kobe Universitygrid.31432.37 Graduate School of Medicine, Kobe, Hyogo, Japan.
Jun AriiDivision of Clinical Virology, Center for Infectious Diseases, Kobe Universitygrid.31432.37 Graduate School of Medicine, Kobe, Hyogo, Japan.ORCID 0000-0002-1689-4016
Lidya Handayani TjanDivision of Clinical Virology, Center for Infectious Diseases, Kobe Universitygrid.31432.37 Graduate School of Medicine, Kobe, Hyogo, Japan.
Mitsuhiro NishimuraDivision of Clinical Virology, Center for Infectious Diseases, Kobe Universitygrid.31432.37 Graduate School of Medicine, Kobe, Hyogo, Japan.
Yasuko MoriDivision of Clinical Virology, Center for Infectious Diseases, Kobe Universitygrid.31432.37 Graduate School of Medicine, Kobe, Hyogo, Japan.ORCID 0000-0002-6595-8522
Kobe University · JP

Funding

Japan Agency for Medical Research and Development (AMED) 20wm0325005hMEXT | Japan Society for the Promotion of Science (JSPS) Grants for Scientific ResearchMinistry of Education, Culture, Sports, Science and Technology (MEXT) 19H05286Ministry of Education, Culture, Sports, Science and Technology (MEXT) Leading Initiative for Excellent Young Researchers GrantMinistry of Education, Culture, Sports, Science and Technology (MEXT) the research fellowshipMSD Life Science Foundation, Public Interest Incorporated Foundation (SD Life Science Foundation)Takeda Science Foundation ( )
6 · The paper itself

Abstract

Viral infection induces host cells to mount a variety of immune responses, which may either limit viral propagation or create conditions conducive to virus replication in some instances. In this regard, activation of the NF-κB transcription factor is known to modulate virus replication. Human herpesvirus 6A (HHV-6A), which belongs to the

Indexed as

Cell LineGene Expression RegulationGenes, ViralGenome, ViralHerpesvirus 6, HumanHumansNeuroinflammatory DiseasesNF-kappa BReceptor, EphB2Roseolovirus InfectionsSignal TransductionViral ProteinsVirus ReplicationEPHB2 protein, humanNF-kappa BReceptor, EphB2Viral Proteinsgene expressionherpesHHV-6NF-κBtegument

Identifiers

PMID34549982
PMCPMC8577390
OpenAlexW3200027581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.