Evidence map›Paper›PMID 34549712›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Lysosomal membrane protein Sidt2 deletion impairs autophagy in human hepatocytes].

M Geng, L Wang, Y Zhang, W Pei, M Qi, M Yang, J Xu, Y Liang, K Lü, C He and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. [Lysosomal membrane proteinNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

M GengDepartment of Endocrinology and Genetic Metabolism, Wannan Medical College, Wuhu 241002, China.
L WangAnhui Provincial Key Laboratory of Biological Macro-molecules Research, Wannan Medical College, Wuhu 241002, China.
Y ZhangAnhui Provincial Key Laboratory of Biological Macro-molecules Research, Wannan Medical College, Wuhu 241002, China.
W PeiAnhui Provincial Key Laboratory of Biological Macro-molecules Research, Wannan Medical College, Wuhu 241002, China.
M QiSchool of Clinical Medicine, Wannan Medical College, Wuhu 241002, China.
M YangSchool of Clinical Medicine, Wannan Medical College, Wuhu 241002, China.
J XuSchool of Clinical Medicine, Wannan Medical College, Wuhu 241002, China.
Y LiangSchool of Clinical Medicine, Wannan Medical College, Wuhu 241002, China.
K LüCentral Laboratory, Wannan Medical College, Wuhu 241002, China.
C HeDepartment of Endocrinology and Genetic Metabolism, Wannan Medical College, Wuhu 241002, China.
J GaoDepartment of Endocrinology and Genetic Metabolism, Wannan Medical College, Wuhu 241002, China.
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of lysosomal membrane protein

methodsCrispr-Cas9 technology was used to construct a human hepatocyte (HL7702) model of

resultsWe successfully constructed a HL7702 cell model of

conclusion

Indexed as

AutophagyHepatocytesNucleotide Transport ProteinsAutophagosomesCells, CulturedGene Knockout TechniquesHumansLysosomal Membrane ProteinsLysosomesLysosomal Membrane ProteinsNucleotide Transport ProteinsSIDT2 protein, humanautophagosomescargo proteinsfusionlysosomesSidt2

Identifiers

PMID34549712
PMCPMC8527224
OpenAlexW3201480621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.