Evidence map›Paper›PMID 34549456›Full record

ArticleThe Journal of dermatology2021

Single-center survey of biologic use for inflammatory skin diseases during the coronavirus disease 2019 pandemic.

Soichiro Kado, Koji Kamiya, Megumi Kishimoto, Takeo Maekawa, Aya Kuwahara, Junichi Sugai, Mayumi Komine, Mamitaro Ohtsuki

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Soichiro KadoDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.ORCID https://orcid.org/0000-0003-3039-8331
Koji KamiyaDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.ORCID https://orcid.org/0000-0002-7938-1947
Megumi KishimotoDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.
Takeo MaekawaDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.ORCID https://orcid.org/0000-0001-5865-8487
Aya KuwaharaDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.
Junichi SugaiDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.
Mayumi KomineDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.ORCID https://orcid.org/0000-0002-1086-1803
Mamitaro OhtsukiDepartment of Dermatology, Jichi Medical University, Shimotsuke, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The ongoing COVID-19 pandemic has affected both daily life and medical care; therefore, the aim of this study was to analyze the use of biologics for inflammatory skin diseases during the COVID-19 pandemic in our hospital. The observation period was between 1 January 2020 and 23 February 2021. In this study, we enrolled 227 patients with psoriasis, six patients with palmoplantar pustulosis (PPP), 69 patients with atopic dermatitis (AD), and five patients with hidradenitis suppurativa (HS). Bioswitch was performed in 25 patients with psoriasis (11.0%). Biologics were discontinued in 14 patients with psoriasis (6.2%), 10 patients with AD (14.5%), and four patients with HS (80.0%); they were not discontinued in patients with PPP. The introduction of biologics was observed in 27 patients with psoriasis (11.9%), four patients with PPP (66.7%), 33 patients with AD (47.8%), and two patients with HS (40.0%). The use of telephone consultations was observed in four patients with psoriasis and two patients with AD. One patient, who received adalimumab for the treatment of psoriatic arthritis, suffered from COVID-19 and recovered after a mild course. In conclusion, we report our experience regarding the use of biologic drugs for inflammatory skin diseases. The use of biologics seemed safe for use amidst COVID-19 infection during the observation period; however, further observation on a larger number of patients is required to confirm the risks and benefits of biologic use in the COVID-19 era.

Indexed as

Biological ProductsCOVID-19PsoriasisHumansPandemicsSARS-CoV-2Biological Productsatopic dermatitiscoronavirus disease 2019hidradenitis suppurativapalmoplantar pustulosispsoriasis

Identifiers

PMID34549456
PMCPMC8652430
OpenAlexW3199969955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.