Evidence map›Paper›PMID 34549417›Full record

ArticleBritish journal of haematology2022

Heart rate variability associated with acute exercise challenge in children with sickle cell anaemia.

Stephan L Kienzle, Mark Rodeghier, Robert I Liem

Open access · bronzeAbstract read
In one paragraph

Article in British journal of haematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stephan L KienzleDivision of Hematology, Oncology, & Stem Cell Transplant, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, USA.ORCID 0000-0002-5189-1056
Mark RodeghierRodeghier Consultants, Chicago, IL, USA.
Robert I LiemDivision of Hematology, Oncology, & Stem Cell Transplant, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, USA.ORCID 0000-0003-2057-3749
Northwestern University · USChicago Cornea Consultants (United States) · US

Funding

The Pro-Inflammatory Effects of Acute Exercise in Children with Sickle Cell Anemia (Diversity Supplement - Olorunyomi - UIC)R01HL136480 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI LIEM, ROBERT IE · 2017 to 2021
$3.0M
NHLBI NIH HHS R01 HL136480
6 · The paper itself

Abstract

We examined heart rate variability (HRV) during exercise testing in 20 children with sickle cell anaemia (SCA) and 12 controls. Subjects achieved lower median HRV at peak exercise [standard deviation of R-wave to R-wave intervals (SDNN), 2·3 vs 2·9 ms, P = 0·027; logarithmic transformation of high frequency power (lnHF), 0·9 vs 1·3 ln(ms

Indexed as

ExerciseHeart RateAdolescentAnalysis of VarianceAnemia, Sickle CellBiomarkersCase-Control StudiesChildElectrocardiographyErythrocyte IndicesExercise TestFemaleHumansMaleYoung AdultBiomarkersautonomic nervous systemexerciseheart rate variabilitypaediatricsickle cell disease

Identifiers

PMID34549417
PMCPMC8755564
OpenAlexW3199451856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.