Evidence map›Paper›PMID 34549305›Full record

ReviewInternational journal of molecular medicine2021

CAPN3: A muscle‑specific calpain with an important role in the pathogenesis of diseases (Review).

Lin Chen, Fajuan Tang, Hu Gao, Xiaoyan Zhang, Xihong Li, Dongqiong Xiao

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  3. Review
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  8. Review
  9. RecurrentInternational journal of molecular sciences · 2025
    Article
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  11. Article
  12. Review
  13. Review
  14. The Potential of Superoxide Dismutase-RichInternational journal of molecular sciences · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lin Chen *Department of Emergency Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Fajuan Tang *Department of Emergency Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Hu GaoDepartment of Emergency Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Xiaoyan ZhangDepartment of Emergency Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Xihong LiDepartment of Emergency Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Dongqiong XiaoDepartment of Emergency Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Sichuan University · CNWest China Second University Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calpains are a family of Ca

Indexed as

AnimalsCalpainEnzyme ActivationHumansModels, BiologicalMuscle, SkeletalMuscular DiseasesOrgan SpecificityCalpainCAPN3limb‑girdle muscular dystrophy type 2Amuscle formationmuscle remodeling

Identifiers

PMID34549305
PMCPMC8480384
OpenAlexW3199610735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.