Evidence map›Paper›PMID 34549145›Full record

ArticleACS omega2021

Fluorescent Carbon Dots as Biosensor, Green Reductant, and Biomarker.

Varsha Raveendran, Renuka Neeroli Kizhakayil

Abstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Carbon Dots: A Review with Focus on Sustainability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Smart green CQD@SiONanoscale advances · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Varsha RaveendranDepartment of Chemistry, University of Calicut, Malappuram, Kerala 673 635, India.
Renuka Neeroli KizhakayilDepartment of Chemistry, University of Calicut, Malappuram, Kerala 673 635, India.ORCID https://orcid.org/0000-0001-6333-5316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon dots, the celebrated green material among the nanocarbon family, are blessed with several interesting features like biocompatibility, solubility, tunable luminescence, and so forth. Herein, carbon dots derived from Mint leaf extract (M-CDs) via a green method are exploited for versatile applications as a biosensor, reductant, and biomarker. M-CDs are applied for fluorimetric sensing of biologically relevant folic acid through quenching response originating from the inner filter effect, with a limit of detection of 280 nM. The carbon dots were highly selective toward folic acid in a collection of 16 biomolecules. The specificity of carbon dots toward folic acid is explained based on the interaction between the two. Along with sensing, herein, we project M-CDs as a green reducing agent by demonstrating the reduction of Fe(III) and noble metal nanoparticle synthesis from their salt solutions. The particles are found to be significantly non-cytotoxic, as evident from the MTT assay performed on primary H8 cells. The application of M-CDs in multicolor imaging is also illustrated using HeLa cells.

Identifiers

PMID34549145
PMCPMC8444300

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.