Evidence map›Paper›PMID 34549071›Full record

ArticleACG case reports journal2021

Rare Variant Hirschsprung Disease Presenting as Large Bowel Obstruction in Adulthood: Hypoganglionosis in the Anorectal Canal.

Roland Y Lee, Huili Li, Rachel V White, Benjamin J Shin, James H Birkholz

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ACG case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Roland Y LeeDepartment of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA.
Huili LiDepartment of Pathology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA.
Rachel V WhiteDepartment of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA.
Benjamin J ShinDepartment of Radiology, Division of Abdominal Imaging, Penn State Health Milton S. Hershey Medical Center, Hershey, PA.
James H BirkholzDepartment of Radiology, Division of Abdominal Imaging, Penn State Health Milton S. Hershey Medical Center, Hershey, PA.
Penn State Milton S. Hershey Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hirschsprung disease (HD) is a congenital bowel innervation disorder characterized by the absence of ganglion cells in the neural plexus of the colorectal wall. Variant HD describes a heterogeneous group of intestinal innervation disorders in which clinical presentation resembles HD despite the presence of ganglion cells seen in rectal biopsies. We present the first reported case of a rare variant HD, hypoganglionosis isolated in the anorectal canal, diagnosed in an adult who presented with a long history of constipation and treated with proctosigmoidectomy with coloanal anastomosis. Histopathology showed rare ganglion cells isolated in the anorectal canal.

Identifiers

PMID34549071
PMCPMC8443806
OpenAlexW3165763225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.