Evidence map›Paper›PMID 34548902›Full record

ArticleProceedings. IEEE International Symposium on Biomedical Imaging2021

HISTOPATHOLOGY IMAGE REGISTRATION BY INTEGRATED TEXTURE AND SPATIAL PROXIMITY BASED LANDMARK SELECTION AND MODIFICATION.

Pangpang Liu, Fusheng Wang, George Teodoro, Jun Kong

Abstract read
In one paragraph

Article in Proceedings. IEEE International Symposium on Biomedical Imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Pangpang LiuDepartment of Mathematics and Statistics, Georgia State University, Atlanta, GA, 30303, USA.
Fusheng WangDepartment of Computer Science, Stony Brook University, Stony Brook, NY, 11794, USA.
George TeodoroDepartment of Computer Science, Federal University of Minas Gerais, Belo Horizonte, 31270, Brazil.
Jun KongDepartment of Mathematics and Statistics, Georgia State University, Atlanta, GA, 30303, USA.

Funding

The RPE and Recovery of the Blood Retina BarrierR01EY028450 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H, GROSSNIKLAUS, HANS E. · 2018 to 2022
$2.4M
Identification and targeting of mechanisms specific to glioma stem cells in glioblastomaR01CA214928 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BRAT, DANIEL J · 2018 to 2022
$1.8M
Computational pathology software for integrative cancer research with three-dimensional digital slidesU01CA242936 · NCI · GEORGIA STATE UNIVERSITY · PI KONG, JUN, WANG, FUSHENG · 2019 to 2021
$1.1M
NCI NIH HHS R01 CA214928NCI NIH HHS U01 CA242936NEI NIH HHS R01 EY028450
6 · The paper itself

Abstract

Three-dimensional (3D) digital pathology has been emerging for next-generation tissue based cancer research. To enable such histopathology image volume analysis, serial histopathology slides need to be well aligned. In this paper, we propose a histopathology image registration fine tuning method with integrated landmark evaluations by texture and spatial proximity measures. Representative anatomical structures and image corner features are first detected as landmark candidates. Next, we identify strong and modify weak matched landmarks by leveraging image texture features and landmark spatial proximity measures. Both qualitative and quantitative results of extensive experiments demonstrate that our proposed method is robust and can further enhance registration accuracy of our previously registered image set by 31.15% (correlation), 4.88% (mutual information), and 41.02% (mean squared error), respectively. The promising experimental results suggest that our method can be used as a fine tuning module to further boost registration accuracy, a premise of histology spatial and morphology analysis in an information-lossless 3D tissue space for cancer research.

Indexed as

histopathology image registrationlandmark evaluationsthree-dimensional pathology

Identifiers

PMID34548902
PMCPMC8452257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.