Evidence map›Paper›PMID 34548877›Full record

ReviewFungal biology reviews2021

The rise in cases of mucormycosis, candidiasis and aspergillosis amidst COVID19.

Asmita Ghosh, Anusua Sarkar, Pubali Paul, Parth Patel

Abstract readReview
In one paragraph

Review in Fungal biology reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Overcoming antifungal resistance inFrontiers in cellular and infection microbiology · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Lower Concentrations of Amphotericin B Combined withAntibiotics (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. An ubiquitous entity of post-COVID rhinomaxillary mucormycosis.Journal of family medicine and primary care · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Asmita GhoshDepartment of Biotechnology, Heritage Institute of Technology, Kolkata 700107, West Bengal, India.
Anusua SarkarDepartment of Biotechnology, Heritage Institute of Technology, Kolkata 700107, West Bengal, India.
Pubali PaulDepartment of Biotechnology, Heritage Institute of Technology, Kolkata 700107, West Bengal, India.
Parth PatelH. K. College of Pharmacy, Jogeshwari West, Mumbai 400102, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Coronavirus outbreak globally has changed the medical system and also led to a shortage of medical facilities in both developing and underdeveloped countries. The COVID19 disease, being novel in nature along with high infectivity and frequent mutational rate, has been termed to be fatal across the globe. The advent of infection by SARS-CoV-2 has brought a myriad of secondary complications and comorbidities resulting in additional challenges to the health care system induced by novel therapeutic procedures. The emerging variant with respect to the Indian subcontinent and the associated genetic mutations have worsened the situation at hand. Proper clinical management along with epidemiological studies and clinical presentations in scientific studies and trials is necessary in order to combat the simultaneous waves of emerging strains. This article summarizes three of the major fungal outbreaks in India namely mucormycosis, candidiasis and aspergillosis, and elaborates their subtypes, pathogenesis, symptoms and treatment and detection techniques. A detail of future therapeutics under consideration are also elaborated along with a general hypothesis on how COVID19 is related to immunological advances leading to major widespread fungal infection in the country. The factors that contribute in promoting virus proliferation and invasive fungal infections include cell-mediated immunity, associated immunocompromised conditions and treatment protocols that slows down immune mechanisms. To better comprehend a fungal or bacterial outbreak, it is very important to conduct audits mediated through multicenter national and state research teams for recognizing patterns and studying current cases of fungal infection in both healthy and comorbid groups of COVID19 patients.

Indexed as

Amphotericin-BAspergillosisCandidiasisCOVID19FungusMucormycosis

Identifiers

PMID34548877
PMCPMC8445778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.