Evidence map›Paper›PMID 34548867›Full record

ArticleJournal of otology2021

Nasopharyngeal colonization of otopathogens in South Indian children with acute otitis media - A case control pilot study.

M Napolean, V Rosemol, M John, A M Varghese, J Periyasamy, V Balaji, P Naina

Open access · diamondAbstract read
In one paragraph

Article in Journal of otology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Human vaccines & immunotherapeutics · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

M NapoleanDepartment of ENT, Christian Medical College, Vellore, Tamil Nadu, India.
V RosemolDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
M JohnDepartment of ENT, Christian Medical College, Vellore, Tamil Nadu, India.
A M VargheseDepartment of ENT, Christian Medical College, Vellore, Tamil Nadu, India.
J PeriyasamyDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
V BalajiDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
P NainaDepartment of ENT, Christian Medical College, Vellore, Tamil Nadu, India.
Christian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute otitis media (AOM) is an inflammatory disease of the middle ear causing significant morbidity in early childhood. A pilot study was undertaken to identify the role of various risk factors South Indian children with AOM, especially the role of nasopharyngeal otopathogens. METHODOLOGY: A prospective case control pilot study was conducted in children aged below six years, presenting to a single tertiary care from 2018 to 2019. Fifty cases with AOM and 45 age and gender matched controls were recruited. Two nasopharyngeal swabs were collected, one was processed for bacterial culture. The other swab was processed according to the CDC recommended broth enrichment method to identify carriage of

resultOtalgia was the major presentation seen in 92% of the children with AOM. None of the clinical and demographic characteristics were found to be statistically significant between the cases and controls. The most common otopathogen was

conclusionThis study strengthens the significant association between nasopharyngeal colonization of otopathogens and AOM as a risk factor that is enhanced by co-colonization.

Indexed as

Acute otitis mediaCase control studyHaemophilus influenzaeMoraxella catarrhalisNasopharyngealOtopathogensStaphylococcus aureusStreptococcus pneumoniae

Identifiers

PMID34548867
PMCPMC8438633
OpenAlexW3133700644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.