Evidence map›Paper›PMID 34548823›Full record

ArticleOpen access rheumatology : research and reviews2021

A Comparison of Demographics, Disease Activity, Disability, and Treatment Among Rheumatoid Arthritis Patients with and without Osteoporosis.

Altaf Abdulkhaliq, Mohamed Cheikh, Fahad Almuntashri, Haneen Alzahrani, Huda Nadwi, Eithar Kadi, Mutasem Abed, Murad Janaini, Alaa Monjed, Nahed Janoudi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open access rheumatology : research and reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Bone Health in Rheumatoid Arthritis: An Update.Current rheumatology reports · 2026
    Review
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Mechanisms of Systemic Osteoporosis in Rheumatoid Arthritis.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Altaf AbdulkhaliqDepartment of Clinical Biochemistry, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0002-8148-1103
Mohamed CheikhInternal Medicine Department, Doctor Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.ORCID 0000-0002-1040-0126
Fahad AlmuntashriDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0003-3689-001X
Haneen AlzahraniDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.
Huda NadwiDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0003-3946-8623
Eithar KadiDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0003-1764-3400
Mutasem AbedDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0002-4621-101X
Murad JanainiDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0002-4082-2127
Alaa MonjedDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.
Nahed JanoudiInternal Medicine Department, Doctor Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.
Hani AlmoallimDepartment of Medicine, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.ORCID 0000-0003-2582-8317
Umm al-Qura University · SASoliman Fakeeh Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOsteoporosis (OP) is one of the most common comorbidities associated with rheumatoid arthritis (RA). Literatures reported that the risk for developing OP was strongly associated with duration and severity of RA. We aim to elaborate on the consequences of OP on disease activity and management plan in patients with RA. PATIENTS AND

methodsA retrospective cohort study recruited 408 patients, including those with RA alone and with RA plus OP. The RA disease activity in the patients was assessed using disease activity score in 28 joints (DAS28-CRP). A statistical analysis was performed to compare data between the two groups of patients and determine any significant risk factor associated with the development of OP in RA patients.

resultsOf 408 patients who were included in this study, 353 patients (86.5%) had only RA, while 55 patients (13.5%) had RA with OP and showed significant difference (

conclusionThere was no significant difference in disease activity at both groups of patients. However, RA with OP group had longer duration of RA, were more frequently treated with steroids, and had greater disability. We recommend physicians focus on controlling RA disease activity, early screening for and treating of OP.

Indexed as

biologicdisease activitydisease modifying antirheumatic drugseffectsosteoporosisRA OPrheumatoid arthritis

Identifiers

PMID34548823
PMCPMC8449680
OpenAlexW3200792176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.