Evidence map›Paper›PMID 34548571›Full record

ArticleScientific reports2021

Use of an endoscopic flexible grasper as a traction tool for excision of polyps: preclinical trial.

Shinya Urakawa, Teijiro Hirashita, Yuka Hirashita, Lea Lowenfeld, Krishna C Gurram, Makoto Nishimura, Jeffrey W Milsom

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Shinya UrakawaDepartment of Surgery, Weill Cornell Medicine/ New York Presbyterian Hospital, 525 East 68th Street, K-801, New York, NY, 10065, USA. urashin.1130@gmail.com.
Teijiro HirashitaDepartment of Surgery, Weill Cornell Medicine/ New York Presbyterian Hospital, 525 East 68th Street, K-801, New York, NY, 10065, USA.
Yuka HirashitaDepartment of Surgery, Weill Cornell Medicine/ New York Presbyterian Hospital, 525 East 68th Street, K-801, New York, NY, 10065, USA.
Lea LowenfeldDepartment of Surgery, Weill Cornell Medicine/ New York Presbyterian Hospital, 525 East 68th Street, K-801, New York, NY, 10065, USA.
Krishna C GurramDepartment of Gastroenterology and Hepatology, The Brooklyn Hospital Center, New York, NY, USA.
Makoto NishimuraGastroenterology, Hepatology and Nutrition Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jeffrey W MilsomDepartment of Surgery, Weill Cornell Medicine/ New York Presbyterian Hospital, 525 East 68th Street, K-801, New York, NY, 10065, USA. milsomj@gmail.com.
Cornell University · USBrooklyn Hospital Center · USMemorial Sloan Kettering Cancer Center · USNewYork–Presbyterian Hospital · USPresbyterian Hospital · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Endoscopic submucosal dissection (ESD) is challenging in the right colon. Traction devices can make it technically easier. In this study, we evaluated a flexible grasper with articulating tip and elbow-like bending (IgE) through a double-balloon surgical platform (DESP), compared with an earlier generation grasper without elbow-like bending (Ig). The reach of Ig/IgE was investigated at eight locations using a synthetic colon within a 3D model. Using a fresh porcine colorectum, 4 cm pseudo-polyps were created at the posterior wall of the ascending colon. Fifty-four ESD procedures were performed using three techniques: standard ESD (STD), ESD using Ig (DESP + Ig), and ESD using IgE (DESP + IgE). IgE was able to reach the full circumference at all the locations, whereas the medial walls proximal to the descending colon were out of Ig's reach. Compared with the STD, both DESP + Ig and DESP + IgE showed significantly shorter procedure time (STD vs. DESP + Ig vs. DESP + IgE = median 48.9 min vs. 38.6 vs. 29.9) and fewer injuries (1.5 vs. 0 vs. 0). Moreover, the DESP + IgE had a shorter procedure time than the DESP + Ig (p = 0.0025). The IgE with DESP increased instrument reach compared to Ig, and likely represented a traction tool for excision of large pseudo-polyps in the right colon.

Indexed as

AnimalsColonic PolypsColonoscopyEndoscopic Mucosal ResectionSwine

Identifiers

PMID34548571
PMCPMC8455611
OpenAlexW3201387512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.