Evidence map›Paper›PMID 34548386›Full record

ArticleJournal of psychiatry & neuroscience : JPN2021

Depressive rumination is correlated with brain responses during self-related processing.

Tzu-Yu Hsu, Tzu-Ling Liu, Paul Z Cheng, Hsin-Chien Lee, Timothy J Lane, Niall W Duncan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychiatry & neuroscience : JPN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Tzu-Yu HsuFrom the Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan (Hsu, Liu, Cheng, Lane, Duncan); the Brain and Consciousness Research Centre, TMU Shuang-Ho Hospital, New Taipei City, Taiwan (Hsu, Cheng, Lane, Duncan); the Institute of Cognitive Neuroscience, National Central University, Zhongda, Taiwan (Liu); the Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Lee); and the Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan (Lee).
Tzu-Ling LiuFrom the Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan (Hsu, Liu, Cheng, Lane, Duncan); the Brain and Consciousness Research Centre, TMU Shuang-Ho Hospital, New Taipei City, Taiwan (Hsu, Cheng, Lane, Duncan); the Institute of Cognitive Neuroscience, National Central University, Zhongda, Taiwan (Liu); the Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Lee); and the Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan (Lee).
Paul Z ChengFrom the Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan (Hsu, Liu, Cheng, Lane, Duncan); the Brain and Consciousness Research Centre, TMU Shuang-Ho Hospital, New Taipei City, Taiwan (Hsu, Cheng, Lane, Duncan); the Institute of Cognitive Neuroscience, National Central University, Zhongda, Taiwan (Liu); the Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Lee); and the Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan (Lee).
Hsin-Chien LeeFrom the Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan (Hsu, Liu, Cheng, Lane, Duncan); the Brain and Consciousness Research Centre, TMU Shuang-Ho Hospital, New Taipei City, Taiwan (Hsu, Cheng, Lane, Duncan); the Institute of Cognitive Neuroscience, National Central University, Zhongda, Taiwan (Liu); the Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Lee); and the Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan (Lee).
Timothy J LaneFrom the Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan (Hsu, Liu, Cheng, Lane, Duncan); the Brain and Consciousness Research Centre, TMU Shuang-Ho Hospital, New Taipei City, Taiwan (Hsu, Cheng, Lane, Duncan); the Institute of Cognitive Neuroscience, National Central University, Zhongda, Taiwan (Liu); the Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Lee); and the Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan (Lee) niall.w.duncan@gmail.com timlane13@gmail.com.
Niall W DuncanFrom the Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan (Hsu, Liu, Cheng, Lane, Duncan); the Brain and Consciousness Research Centre, TMU Shuang-Ho Hospital, New Taipei City, Taiwan (Hsu, Cheng, Lane, Duncan); the Institute of Cognitive Neuroscience, National Central University, Zhongda, Taiwan (Liu); the Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (Lee); and the Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan (Lee) niall.w.duncan@gmail.com timlane13@gmail.com.
National Central University · TWTaipei Medical University-Shuang Ho Hospital · TWTaipei Medical University · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRumination, a tendency to focus on negative self-related thoughts, is a central symptom of depression. Studying the self-related aspect of such symptoms is challenging because of the need to distinguish self effects from the emotional content of task stimuli. This study employed an emotionally neutral self-related paradigm to investigate possible altered self-processing in depression and its link to rumination.

methodsPeople with major depressive disorder (

resultsParticipants with major depressive disorder displayed a difference in late positive potentials across frontocentral electrodes between self-related and non-self-related conditions. We found no such difference in controls. The magnitude of this difference was positively correlated with depressive symptoms and reported rumination. Participants with major depressive disorder also had elevated theta oscillation power at central electrodes in self-related conditions, a finding that we did not see in controls. LIMITATIONS: Patients with major depressive disorder were medicated at the time of the study. The group studied was primarily female, so the observed effects may have been sex-specific.

conclusionRumination appears to be linked to altered self-related processing in depression, independent of stimuli-related emotional confounds. This connection between self-related processing and depression may point to a self disorder as a core component of depression.

Indexed as

Rumination, CognitiveAdultBrainEmotionsFemaleHumansMajor Depressive DisorderMale

Identifiers

PMID34548386
PMCPMC8526127
OpenAlexW3201198833

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.