SynthesisBMJ open2021
Anxiety and depression among healthcare workers during the COVID-19 pandemic: a systematic umbrella review of the global evidence.
Synthesis in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
63 citing papers in PubMed, 9 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- Organizational interventions to support and promote the mental health of healthcare workers during pandemics and epidemics: a systematic review.BMC health services research · 2025Pooled it
- Identification and classification of risk factors for mental health problems in healthcare workers using a systemic framework: an umbrella review.BMC public health · 2025Pooled it
- Sedentary behaviors and physical activity of the working population measured by accelerometry: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Global prevalence of perinatal depression and anxiety during the COVID-19 pandemic: An umbrella review and meta-analytic synthesis.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
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- Global burden of mental health problems among children and adolescents during COVID-19 pandemic: An umbrella review.Psychiatry research · 2022Pooled it
- A systematic review of the evidence relating to disclosure of psychological distress by mental health professionals within the workplace.Journal of clinical psychology · 2022Pooled it
- Prevalence of Depression and Anxiety in Nurses during the First Eleven Months of the COVID-19 Pandemic: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Psychological distress and Africentric coping strategies among nurses in Ghana: prevalence, correlates and predictors.BMC nursing · 2026Article
- Coping profiles and their association with vicarious post-traumatic growth among nurses during the three waves of the COVID-19 pandemic.Journal of clinical nursing · 2025Article
- An Umbrella Review of Quality of Life Among the General Population During the COVID-19 Pandemic.Journal of clinical medicine · 2025Review
- Network analysis of burnout, depression, and anxiety with occupational and personal outcomes among clinical nurses in China.Scientific reports · 2025Article
- The mediating role of spirituality in the relationship between occupational stress and satisfaction with life among nurses.BMC nursing · 2025Article
- The Relationship Between Spirituality, Stress, and Depression Among Health Professionals in Greece.Healthcare (Basel, Switzerland) · 2025Article
- [Mental distress of intensive care staff in Germany during the COVID-19 pandemic. Results from the VOICE study].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Article
- Photobiomodulation: shining a light on depression.Theranostics · 2025Review
- Anxiety and stress among Vietnamese health workers during the emergence of the SARS-CoV-2 Omicron variant: a cross-sectional study.Journal of medicine and life · 2024Article
- Understanding the mental health and intention to leave of the public health workforce in Canada during the COVID-19 pandemic: A cross-sectional study.BMC public health · 2024Article
- Compassion Fatigue in a Cohort of South Italian Nurses and Hospital-Based Clinical Social Workers Following COVID-19: A Cross-Sectional Survey.Journal of clinical medicine · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo summarise the evidence relating to the prevalence of anxiety and depression among healthcare workers (HCWs) during the COVID-19 pandemic.
designAn umbrella review of systematic reviews was undertaken using the Joanna Briggs Institute (JBI) methods. DATA SOURCES: The Cochrane database of systematic reviews, JBI Evidence Synthesis, MEDLINE, Web of Science, PsycINFO, Embase and CINAHL were searched in March 2021 for reviews published in English. ELIGIBILITY CRITERIA: Systematic reviews reporting the prevalence of anxiety and depression among HCWs during the COVID-19 pandemic. Two researchers screened each abstract and independently reviewed full text articles. Study quality was assessed using the JBI critical appraisal tool for systematic reviews, and the degree of overlap in primary studies was calculated.
resultsTen systematic reviews (100 unique studies), including 169 157 HCWs from 35 countries were included. The prevalence of anxiety among all HCWs ranged from 22.2% (95% CI 21.3% to 23.1%) to 33.0% (95% CI 31.9% to 34.1%). The prevalence of anxiety among physicians (n=5820) was reported to be between 17% and 19.8% and for nurses (n=14 938) between 22.8% and 27%. The prevalence of depression among all HCWs ranged from 17.9% (95% CI 17.1% to 18.8%) to 36% (95% CI 34.9% to 37.1%). The prevalence of depression among physicians (n=643) and nurses (n=8063) was reported to be 40.4% and 28%, respectively.
conclusionsThere is wide variation evident in the presence of anxiety and depression among HCWs. In particular, the prevalence of depression among physicians was high. Strategies to reduce the incidence of anxiety and depression are urgently required. PROSPERO REGISTRATION NUMBER: CRD42021238960.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.