Evidence map›Paper›PMID 34548137›Full record

ReviewCritical care clinics2021

Acute Respiratory Distress Syndrome: Ventilator Management and Rescue Therapies.

Melissa H Coleman, J Matthew Aldrich

Abstract readReview
In one paragraph

Review in Critical care clinics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Characteristics and temporality of the ventilatory techniques in the management of acute respiratory distress syndrome: A scoping review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Melissa H ColemanDivision of Cardiothoracic Surgery, Department of Surgery, Critical Care Medicine, University of California, San Francisco, 500 Parnassus Avenue, MUW-405, Box 0118, San Francisco, CA 94143, USA.
J Matthew AldrichDepartment of Anesthesia and Perioperative Care, Critical Care Medicine, University of California, San Francisco, 505 Parnassus Avenue, M917, San Francisco, CA 94143, USA. Electronic address: matt.aldrich@ucsf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review describes the management of mechanical ventilation in patients with acute respiratory distress syndrome, including in those with coronavirus disease 2019. Low tidal volume ventilation with a moderate to high positive end-expiratory pressure remains the foundation of an evidence-based approach. We consider strategies for setting positive end-expiratory pressure levels, the use of recruitment maneuvers, and the potential role of driving pressure. Rescue therapies including prone positioning and extracorporeal membrane oxygenation are also discussed.

Indexed as

COVID-19Respiratory Distress SyndromeHumansRespiration, ArtificialSARS-CoV-2Ventilators, MechanicalAcute respiratory distress syndromeCOVID-19Driving pressureExtracorporeal membrane oxygenationLung protective ventilationOpen lung approachProne positioning

Identifiers

PMID34548137
PMCPMC8157117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.