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ArticleBMC public health2021

Use of methamphetamine and alcohol among people with opioid use disorder and HIV in Vietnam: a qualitative study.

Andrew Edsall, Kim A Hoffman, Dinh Thanh Thuy, Pham Phuong Mai, Nguyen Thu Hang, Tong Thi Khuyen, Nguyen Thu Trang, Lynn E Kunkel, Le Minh Giang, P Todd Korthuis

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01936857 (Buprenorphine to Improve HIV Care Engagement and Outcomes), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01936857 phase4completednot on this map

Buprenorphine to Improve HIV Care Engagement and Outcomes: A Randomized Trial (BRAVO)

TypeinterventionalSponsorOregon Health and Science UniversityRan2015 to 2019Enrolled281ConditionsHIV, Substance Related DisordersArmsBuprenorphine/naloxone, Methadone Maintenance Therapy
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Andrew EdsallOregon Health & Science University School of Medicine, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA. edsall.andrew@gmail.com.
Kim A Hoffman *Oregon Health & Science University - Portland State University School of Public Health, 840 SW Gaines St, Room 230, Portland, OR, 97239, USA.
Dinh Thanh ThuyHanoi Medical University, 1 Tôn Thất Tùng, Kim Liên, Đống Đa, Hà Nội, 116001, Vietnam.
Pham Phuong MaiHanoi Medical University, 1 Tôn Thất Tùng, Kim Liên, Đống Đa, Hà Nội, 116001, Vietnam.
Nguyen Thu HangOregon Health & Science University - Portland State University School of Public Health, 840 SW Gaines St, Room 230, Portland, OR, 97239, USA.
Tong Thi KhuyenHanoi Medical University, 1 Tôn Thất Tùng, Kim Liên, Đống Đa, Hà Nội, 116001, Vietnam.
Nguyen Thu TrangHanoi Medical University, 1 Tôn Thất Tùng, Kim Liên, Đống Đa, Hà Nội, 116001, Vietnam.
Lynn E KunkelOregon Health & Science University - Portland State University School of Public Health, 840 SW Gaines St, Room 230, Portland, OR, 97239, USA.
Le Minh Giang *Hanoi Medical University, 1 Tôn Thất Tùng, Kim Liên, Đống Đa, Hà Nội, 116001, Vietnam.
P Todd Korthuis *Oregon Health & Science University School of Medicine, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA.
Portland State University · USOregon Health & Science University · US

Funding

Buprenorphine to Improve HIV Care Engagement and Outcomes: A Randomized TrialR01DA037441 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KORTHUIS, PHILIP TODD · 2013 to 2018
$2.7M
NIDA NIH HHS R01 DA037441
6 · The paper itself

Abstract

backgroundHeroin use continues to drive HIV transmission in Vietnam, but methamphetamine and alcohol use are growing rapidly and, as in other countries, polysubstance use is widespread. The objective of this study was to understand the interplay between heroin, methamphetamine, and alcohol use among people with opioid use disorder (OUD) and HIV in Vietnam.

methodsWe conducted 44 in-depth, face-to-face qualitative interviews with people with OUD and HIV who participated in the BRAVO trial of buprenorphine versus methadone in five Vietnam HIV clinics. Interviews probed participants' experiences of heroin, methamphetamine, and alcohol use and their interplay with HIV/OUD treatment. Interviews were professionally transcribed and analyzed using a thematic analysis approach.

resultsOf 44 participants interviewed 42 were male, on average 38.8 years of age, with 30 reporting a history of methamphetamine use and 33 reporting a history of alcohol use. Several themes emerged: 1) Methamphetamine and alcohol were perceived to have lower addiction potential than heroin 2) Social settings were key facilitators of alcohol and methamphetamine use 3) Some participants, but not all, used methamphetamine to help quit heroin 4) Consuming alcohol blunted the effects of heroin, while paradoxically serving as a catalyst for heroin use 5) Use of methamphetamine was perceived by many participants to be incompatible with treatment for HIV.

conclusionsParticipant experiences reflected a significant impact of polysubstance use on treatment of HIV and OUD. Patterns of polysubstance use are subject to common preconceptions of alcohol and methamphetamine as having a low addictive potential, and these substances are deeply enmeshed in the social life of many people with OUD in Vietnam. Interventions to address complex social norms and potential harms of polysubstance use are urgently needed as the population of people receiving medication for OUD (MOUD) increases in Vietnam and globally.

trial registrationBRAVO - NCT01936857 , September 2013.

Indexed as

HIV InfectionsMethamphetamineOpioid-Related DisordersHumansMaleMethadoneVietnamMethadoneMethamphetamineAlcoholHeroinHIVMedication for opioid use disorderMethamphetamineVietnam

Identifiers

PMID34548042
PMCPMC8456677
OpenAlexW3199149417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.