Evidence map›Paper›PMID 34548012›Full record

ArticleBMC cardiovascular disorders2021

ST-segment resolution as a marker for severe myocardial fibrosis in ST-segment elevation myocardial infarction.

Qian Dong, Xuesong Wen, Guanglei Chang, Rui Xia, Sihang Wang, Yunjing Yang, Yi Tao, Dongying Zhang, Shu Qin

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qian DongDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Xuesong WenChongqing Medical University, Yuzhong, Chongqing, China.
Guanglei ChangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Rui XiaDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Sihang WangDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Yunjing YangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Yi TaoChongqing Medical University, Yuzhong, Chongqing, China.
Dongying ZhangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China. zhangdongying@cqmu.edu.cn.
Shu QinDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China. 1296224271@qq.com.
Chongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between ST-segment resolution (STR) and myocardial scar thickness after percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI).

methodsForty-two STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured at emergency admission and at 24 h after PCI. Late gadolinium-enhanced cardiac magnetic resonance imaging (CMR-LGE) was performed 7 days after PCI to evaluate myocardial scars. Statistical analyses were performed to assess the utility of STR to predict the development of transmural (> 75%) or non-transmural (< 75%) myocardial scars, according to previous study.

resultsThe sensitivity and specificity of STR for predicting transmural scars were 96% and 88%, respectively, at an STR cut-off value of 40.15%. The area under the curve was 0.925. Multivariate logistic proportional hazards regression analysis disclosed that patients with STR < 40.15% had a 170.90-fold higher probability of developing transmural scars compared with patients with STR ≥ 40.15%. Pearson correlation and linear regression analyses showed STR percentage was significantly associated with myocardial scar thickness and size.

conclusionSTR < 40.15% at 24 h after PCI may provide meaningful diagnostic information regarding the extent of myocardial scarification in STEMI patients.

Indexed as

ElectrocardiographyMagnetic Resonance ImagingAgedCoronary OcclusionCoronary StenosisCross-Sectional StudiesFemaleFibrosisHumansMaleMiddle AgedMyocardiumPercutaneous Coronary InterventionPredictive Value of TestsReproducibility of ResultsST Elevation Myocardial InfarctionMyocardial scarPercutaneous coronary interventionST-elevation myocardial infarctionST-segment resolution

Identifiers

PMID34548012
PMCPMC8454141
OpenAlexW3171151319

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.