Evidence map›Paper›PMID 34547971›Full record

ReviewRenal failure2021

MicroRNAs in IgA nephropathy.

Xingchen Yao, Yaling Zhai, Huanping An, Jingge Gao, Yazhuo Chen, Wenhui Zhang, Zhanzheng Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Construction of aRenal failure · 2024
    Article
  6. Article
  7. Review
  8. Contemporary review of IgA nephropathy.Frontiers in immunology · 2024
    Review
  9. An Update on the Genetics of IgA Nephropathy.Journal of clinical medicine · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. The role of N6-methyladenosine (mFrontiers in medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xingchen YaoDepartment of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yaling ZhaiDepartment of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Huanping AnMedicine Experiment Center, Hanzhong Vocational and Technical College, Hanzhong, China.
Jingge GaoDepartment of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yazhuo ChenDepartment of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wenhui ZhangDepartment of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhanzheng ZhaoDepartment of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. It is considered that the pathogenesis of IgAN involves the 'multiple hit theory' and the immune-inflammatory mechanism; however, these theories have certain limitations. The gold standard for diagnosing IgAN is still renal biopsy. Although renal biopsy is accurate, it is traumatic and is associated with some risks and limitations, so there is a need for non-invasive diagnostic methods. According to recent studies, microRNAs (miRNAs) play important roles in the occurrence and development of IgAN; thus, they provide the possibility of the noninvasive diagnosis of IgAN and also have some value in predicting prognosis. This review summarizes the current research status of miRNAs in the occurrence, development, diagnosis, and prognosis of IgAN. We also highlight some interesting and challenging points that require further study.

Indexed as

BiomarkersGlomerulonephritis, IGAHumansMicroRNAsNephritis, InterstitialPrognosisSeverity of Illness IndexBiomarkersMicroRNAsdiagnosisIgA nephropathyMicroRNApathogenesisprognosis

Identifiers

PMID34547971
PMCPMC8462925
OpenAlexW3199002557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.