Evidence map›Paper›PMID 34547464›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2022

METTL3-m

Zishan Peng, Yingying Gong, Xuejie Wang, Weiman He, Liting Wu, Luyao Zhang, Li Xiong, Yanrui Huang, Lei Su, Peijie Shi and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 104 citations in OpenAlex.

  1. Dysregulated mScience advances · 2026
    Article
  2. Article
  3. mNature reviews. Neuroscience · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. mInternational journal of molecular medicine · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. NBiomolecules · 2026
    Review
  15. Article
  16. Article
  17. Autophagy in the liver.Autophagy reports · 2026
    Review
  18. Article
  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Zishan PengDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Yingying GongDepartment of Geriatrics, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Xuejie WangDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Weiman HeDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Liting WuDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Luyao ZhangDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Li XiongDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Yanrui HuangDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Lei SuDepartment of Geriatrics, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Peijie ShiDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Xiaopei CaoDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Rengyun LiuInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Yanbing LiDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China.
Haipeng XiaoDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan Road 2, Guangzhou 510080, China. Electronic address: xiaohp@mail.sysu.edu.cn.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyladenosine (m

Indexed as

Non-alcoholic Fatty Liver DiseaseAdenosineAnimalsAutophagyIntracellular Signaling Peptides and ProteinsMethylationMethyltransferasesMiceRNA-Binding ProteinsAdenosineIntracellular Signaling Peptides and ProteinsMethyltransferasesMettl3 protein, mouseRNA-Binding ProteinsRubcn protein, mouseYthdf1 protein, mouseautophagym(6)A modificationMETTL3NAFLDYTHDF1

Identifiers

PMID34547464
PMCPMC8821937
OpenAlexW3199001105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.