SynthesisJournal of studies on alcohol and drugs2021
The "Outcome Reporting in Brief Intervention Trials: Alcohol" (ORBITAL) Core Outcome Set: International Consensus on Outcomes to Measure in Efficacy and Effectiveness Trials of Alcohol Brief Interventions.
Synthesis in Journal of studies on alcohol and drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effectiveness of Alcohol Use Disorder Pharmacotherapies by Sex: Systematic Review and Meta-Analysis.Drug and alcohol review · 2026Pooled it
- Mindfulness-Based Interventions for Adolescent Substance Use and Substance Use Disorders: A Systematic Review.Pediatrics · 2026Pooled it
- Review article: Electronic screening and brief intervention for alcohol-related trauma: A systematic review and meta-analysis.Emergency medicine Australasia : EMA · 2025Pooled it
- Practitioner and digitally delivered interventions for reducing hazardous and harmful alcohol consumption in people not seeking alcohol treatment: a systematic review and network meta-analysis.Addiction (Abingdon, England) · 2023Pooled it
- A Rapid Systematic Review of Worldwide Alcohol Use Disorders and Brief Alcohol Interventions in the Criminal Justice System.Frontiers in psychiatry · 2022Pooled it
- Brief Intervention Versus More Extensive Treatment for Alcohol Use Disorder (AUD): Testing the Comparability Hypothesis.Journal of studies on alcohol and drugs · 2026Trial
- Effectiveness of the Components of a Digital Multiple Health Behavior Change Intervention Among Individuals Seeking Help Online (Coach): Factorial Randomized Trial.Journal of medical Internet research · 2026Trial
- Effectiveness of the Components of a Digital Multiple Health Behavior Intervention Among University Students (Buddy): Factorial Randomized Trial.Journal of medical Internet research · 2026Trial
- Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- The effectiveness of a brief intervention for intensive care unit patients with hazardous alcohol use: a randomized controlled trial.Critical care (London, England) · 2024Trial
- Comparative feasibility and preliminary efficacy of CBT for insomnia among adults seeking and not seeking addiction treatment.Journal of sleep research · 2024Trial
- Effect of a smartphone intervention as a secondary prevention for use among university students with unhealthy alcohol use: randomised controlled trial.BMJ (Clinical research ed.) · 2023Trial
- Public knowledge, beliefs and behaviours related to antimicrobial resistance and antibiotics: a systematic review of studies in high-income countries.JAC-antimicrobial resistance · 2026Review
- The measurement of harm reduction goals and outcomes for substance use: Current state and future directions.Journal of prevention and health promotion · 2026Article
- Reducing alcohol-associated liver disease burden in the general population.The lancet. Gastroenterology & hepatology · 2025Review
- A Meta-Analysis of Bi-Directional Associations between Sleep Health and Substance Use among U.S. Youth: Racial/Ethnic Differences.Current addiction reports · 2025Article
- Questionable generalizability of Alcohol Use Disorders Identification Test-Consumption scoring warrants caution when used for outcome monitoring: Evidence from simulated and real-world trial data.Addiction (Abingdon, England) · 2025Article
- Article
- Socio-economic equity in the impact of population-based interventions to reduce alcohol consumption.The Cochrane database of systematic reviews · 2025Article
- Associations between clinical AUDIT-C screens and HDL cholesterol are observed across primary care patient subgroups.Alcohol, clinical & experimental research · 2025Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
objectiveThe purpose of this study was to report the "Outcome Reporting in Brief Intervention Trials: Alcohol" (ORBITAL) recommended core outcome set (COS) to improve efficacy and effectiveness trials/evaluations for alcohol brief interventions (ABIs).
methodA systematic review identified 2,641 outcomes in 401 ABI articles measured by 1,560 different approaches. These outcomes were classified into outcome categories, and 150 participants from 19 countries participated in a two-round e-Delphi outcome prioritization exercise. This process prioritized 15 of 93 outcome categories for discussion at a consensus meeting of key stakeholders to decide the COS. A psychometric evaluation determined how to measure the outcomes.
resultsTen outcomes were voted into the COS at the consensus meeting: (a) typical frequency, (b) typical quantity, (c) frequency of heavy episodic drinking, (d) combined consumption measure summarizing alcohol use, (e) hazardous or harmful drinking (average consumption), (f) standard drinks consumed in the past week (recent, current consumption), (g) alcohol-related consequences, (h) alcohol-related injury, (i) use of emergency health care services (impact of alcohol use), and (j) quality of life.
conclusionsThe ORBITAL COS is an international consensus standard for future ABI trials and evaluations. It can improve the synthesis of new findings, reduce redundant/selective reporting (i.e., reporting only some, usually significant outcomes), improve between-study comparisons, and enhance the relevance of trial and evaluation findings to decision makers. The COS is the recommended minimum and does not exclude other, additional outcomes.
Indexed as
Identifiers
34546911PMC8819610What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.