Evidence map›Paper›PMID 34546847›Full record

ArticleBioengineered2021

Protective effects of Schisandrin B against D-GalN-induced cell apoptosis in human hepatocyte (L02) cells via modulating Bcl-2 and Bax.

Yanwu Hu, Haitao Li, Ruili Li, Yue Tian, Zijing Wu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yanwu HuSchool of Medicine, Tonghua Normal University, Tonghua, China.ORCID 0000-0002-9891-2491
Haitao LiDepartment of Pharmacy, Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, China.
Ruili LiDepartment of Pharmacy, Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, China.
Yue TianSchool of Medicine, Tonghua Normal University, Tonghua, China.
Zijing WuSchool of Medicine, Tonghua Normal University, Tonghua, China.
Tonghua Normal University · CNChangchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schisandrin B is a dibenzocyclooctadiene derivative extracted from

Indexed as

Apoptosisbcl-2-Associated X ProteinCell LineCyclooctanesGalactosamineHepatocytesHumansLignansPolycyclic CompoundsProtective AgentsProto-Oncogene Proteins c-bcl-2BAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanCyclooctanesGalactosamineLignansPolycyclic CompoundsProtective AgentsProto-Oncogene Proteins c-bcl-2schizandrin BapoptosisBaxBcl-2D-GalN-inducedhuman hepatocyte cellsschisandrin B

Identifiers

PMID34546847
PMCPMC8806808
OpenAlexW3201531078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.