Evidence map›Paper›PMID 34546608›Full record

ArticleDermatologic therapy2021

Leukocytoclastic vasculitis as a cutaneous manifestation of ChAdOx1 nCoV-19 corona virus vaccine (recombinant).

Sunmeet Sandhu, Anuj Bhatnagar, Harish Kumar, Prashant Kumar Dixit, Gourang Paliwal, Devinder Kumar Suhag, Chetan Patil, Debdeep Mitra

Abstract read
In one paragraph

Article in Dermatologic therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunmeet SandhuDepartment of Dermatology, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.ORCID 0000-0002-9222-4006
Anuj BhatnagarDepartment of Dermatology, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.
Harish KumarDepartment of Medicine, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.
Prashant Kumar DixitDepartment of Medicine, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.
Gourang PaliwalDepartment of Pathology, Armed Forces Medical College, Pune, Maharashtra, India.
Devinder Kumar SuhagDepartment of Dermatology, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.
Chetan PatilDepartment of Dermatology, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.
Debdeep MitraDepartment of Dermatology, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the present COVID-19 vaccination drive across the world, adverse skin reactions post COVID-19 vaccine is expected. Majority of these reactions seen were transient or local injection site reactions. However, as the larger population is being vaccinated, certain uncommon dermatological presentations including leukocytoclastic vasculitis, pityriasis rosea, and exacerbation of pre-existing autoimmune diseases are now being reported. Among all the COVID-19 vaccines, most of these reactions are seen with messenger ribonucleic acid-based Pfizer/BioNTech (BNT162b2) and Moderna (mRNA-1273) vaccine. We report two cases of leukocytoclastic vasculitis following ChAdOx1 nCoV-19 corona virus vaccine (recombinant) that bring out potential new dermatological manifestations of recombinant corona virus vaccine being administered across the European, South American, and Asian countries. It is important for all health care workers and patients to be aware of the corona virus vaccine associated adverse cutaneous reactions.

Indexed as

COVID-19Skin Diseases2019-nCoV Vaccine mRNA-1273BNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesHumansSARS-CoV-2Vasculitis, Leukocytoclastic, Cutaneous2019-nCoV Vaccine mRNA-1273BNT162 VaccineChAdOx1 nCoV-19COVID-19 Vaccinescorona virus vaccine (recombinant)COVID-19COVID-19 vaccinationleukocytoclastic vasculitis

Identifiers

PMID34546608
PMCPMC8646583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.