Evidence map›Paper›PMID 34546492›Full record

ArticleBiological trace element research2022

Anticancer Effects of Vitis vinifera L. Mediated Biosynthesized Silver Nanoparticles and Cotreatment with 5 Fluorouracil on HT-29 Cell Line.

Giray Salman, Suray Pehlivanoglu, Cigdem Aydin Acar, Sukriye Yesilot

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Antioxidant and Anticancer Activity ofLife (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Apoptotic effects of3 Biotech · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Giray SalmanDepartment of Health and Biomedical Sciences, Burdur Mehmet Akif Ersoy University, Burdur, Turkey.ORCID http://orcid.org/0000-0002-1602-992X
Suray PehlivanogluDepartment of Molecular Biology and Genetics, Necmettin Erbakan University, Konya, Turkey.ORCID http://orcid.org/0000-0001-7422-2974
Cigdem Aydin AcarDepartment of Health and Biomedical Sciences, Burdur Mehmet Akif Ersoy University, Burdur, Turkey.ORCID http://orcid.org/0000-0002-1311-2314
Sukriye YesilotDepartment of Health and Biomedical Sciences, Burdur Mehmet Akif Ersoy University, Burdur, Turkey. syesilot@mehmetakif.edu.tr.ORCID http://orcid.org/0000-0003-3354-8489
Burdur Mehmet Akif Ersoy Üniversitesi · TRNecmettin Erbakan University · TR

Funding

Burdur Mehmet Akif Ersoy University Scientific Research Projects Unit [Project number: 0594-YL-19]
6 · The paper itself

Abstract

The aim of this study was to evaluate the anticancer effects of biosynthesized silver nanoparticles (Vv-AgNPs) from grape (Vitis vinifera L.) seed aqueous extract, alone or in combination with 5-Fluorouracil (5-FU) on HT-29 cell line. Vv-AgNPs were characterized by techniques such as UV-vis spectrophotometer (surface plasmon peak 454 nm), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). HT-29 cells were treated with different concentrations (0-80 μg/mL for MTT) and (0-20 μg/mL for BrdU) of Vv-AgNPs alone and combined with (200 μg/mL) 5-FU for 72 h. The cytotoxic effects were analyzed by [3-(4,5-dimethylthiazol-2- yl)-2,5-diphenyl tetrazolium bromide] (MTT) assay (IC

Indexed as

Antineoplastic AgentsMetal NanoparticlesVitisBromodeoxyuridineFluorouracilHT29 CellsHumansPlant ExtractsSilverTumor Suppressor Protein p53Antineoplastic AgentsBromodeoxyuridineFluorouracilPlant ExtractsSilverTumor Suppressor Protein p535-FluorouracilColon cancerGreen synthesisHT-29 cell lineSilver nanoparticles

Identifiers

PMID34546492
OpenAlexW3199095119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.