Evidence map›Paper›PMID 34546447›Full record

SynthesisArchives of osteoporosis2021

Exercise for improving age-related hyperkyphosis: a systematic review and meta-analysis with GRADE assessment.

Matteo Ponzano, Nicholas Tibert, Symron Bansal, Wendy Katzman, Lora Giangregorio

Erratum issuedAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effect of Therapeutic Exercise on the Management of Hyperkyphosis in Adolescence and Young Adulthood: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Pooled it
  2. Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Guideline
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  13. Review
  14. Article
  15. International consensus on the non-pharmacological and non-surgical management of osteoporotic vertebral fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Article
  16. Article
  17. The Association Between the Kyphosis Angle and Physical Performance in Community-Dwelling Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Matteo PonzanoDepartment of Kinesiology, University of Waterloo, Waterloo, Canada.
Nicholas TibertDepartment of Kinesiology, University of Waterloo, Waterloo, Canada.
Symron BansalDepartment of Kinesiology, University of Waterloo, Waterloo, Canada.
Wendy KatzmanDepartment of Physical Therapy and Rehabilitation Science, University of California San Francisco, San Francisco, USA.
Lora GiangregorioDepartment of Kinesiology, University of Waterloo, Waterloo, Canada. lora.giangregorio@uwaterloo.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reviewed exercise trials in men and women ≥ 45 years with hyperkyphosis at the baseline and performed meta-analyses for kyphosis and health-related outcomes. PURPOSE: To determine the effects of exercise interventions on kyphosis angle, back extensor muscle strength or endurance, physical functioning, quality of life, pain, falls, and adverse events in adults 45 years or older with hyperkyphosis.

methodsMultiple databases were searched to May 2020. Randomized controlled trials (RCTs), non-RCT, and pre-post intervention studies that had at least one group with a mean kyphosis angle of at least 40° at the baseline were included.

resultsTwenty-four studies were included. Exercise or physical therapy improved kyphosis outcomes (SMD - 0.31; 95% confidence intervals [CI] - 0.46, - 0.16; moderate certainty evidence), back extensor muscle strength (MD 10.51 N; 95% CI 6.65, 14.38; very low certainty evidence), and endurance (MD 9.76 s; 95% CI 6.40, 13.13; low certainty evidence). Meta-analyses showed improvements in health-related quality of life (HRQoL) (SMD 0.21; 95% CI 0.06, 0.37; moderate certainty of evidence), general pain (MD - 0.26; 95% CI - 0.39, - 0.13; low certainty of evidence), and performance on the timed up and go (TUG) test (MD - 0.28 s; 95% CI - 0.48, - 0.08; very low certainty of evidence). The effects on the rate of falls (incidence rate ratio [IRR] 1.15; 95% CI 0.64, 2.05; low certainty evidence) or minor adverse events (IRR 1.29; 95% CI 0.95, 1.74; low certainty evidence) are uncertain. No serious adverse events were reported in the included studies.

conclusionsInterventions targeting hyperkyphosis may improve kyphosis outcomes in adults with hyperkyphosis.

Indexed as

GRADE ApproachKyphosisAdultExerciseFemaleHumansMaleMuscle StrengthQuality of LifeExercise interventionsKyphosisPosture

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.