Evidence map›Paper›PMID 34546401›Full record

ReviewDer Internist2021

[Severe secondary sclerosing cholangitis as manifestation of a very rare underlying disease].

Britta Franziska Zecher, Roman Zenouzi, Melanie Lang, Panagiotis Karagiannis, Till Clauditz, Lutz Fischer, Martina Sterneck, Christoph Schramm, Ansgar W Lohse, Marcial Sebode

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Der Internist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Britta Franziska ZecherI. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Roman ZenouziI. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Melanie LangUniversitäres Transplantations Centrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Panagiotis KaragiannisII. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Till ClauditzInstitut für Pathologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Lutz FischerUniversitäres Transplantations Centrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Martina SterneckI. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Christoph SchrammI. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Ansgar W LohseI. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Marcial SebodeI. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. m.sebode@uke.de.
University Medical Center Hamburg-Eppendorf · DEUniversität Hamburg · DEERN RARE-LIVER

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a very rare cause of secondary sclerosing cholangitis. We report the case of a 42-year-old male patient with sclerosing cholangitis and histological evidence of LCH from a bile duct biopsy. Due to rapid disease progression and exhaustion of conservative therapeutic approaches the patient received a liver transplantation. Nearly 2 years after transplantation the patient has a good graft function and no signs of recurrence of the underlying LCH.

Indexed as

Cholangitis, SclerosingHistiocytosis, Langerhans-CellLiver TransplantationAdultBiopsyHumansMaleRare DiseasesCholangiography, endoscopic retrogradeCholangitis, sclerosing, secondaryHistiocytosis, Langerhans cellLiver transplantationUnclear cholestasis

Identifiers

PMID34546401
OpenAlexW3200436032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.