Evidence map›Paper›PMID 34546072›Full record

ArticlemSystems2021

Genomic Stability and Genetic Defense Systems in

Stephany Flores Ramos, Silvio D Brugger, Isabel Fernandez Escapa, Chelsey A Skeete, Sean L Cotton, Sara M Eslami, Wei Gao, Lindsey Bomar, Tommy H Tran, Dakota S Jones and 4 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. D-alanine aminotransferase (Dat) promotesbioRxiv : the preprint server for biology · 2026
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  3. Association of nasopharyngealMicrobiology spectrum · 2026
    Article
  4. bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Complete genome sequence ofMicrobiology resource announcements · 2025
    Article
  7. Article
  8. Complete genome sequence forMicrobiology resource announcements · 2025
    Article
  9. Article
  10. Article
  11. Computational and in vitro evaluation of probiotic treatments for nasalProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. Description of two novelbioRxiv : the preprint server for biology · 2024
    Article
  15. Metabolic capabilities are highly conserved among human nasal-associatedbioRxiv : the preprint server for biology · 2024
    Article
  16. International journal of systematic and evolutionary microbiology · 2024
    Article
  17. Article
  18. Frontiers in microbiomes · 2024
    Article
  19. Article
  20. International journal of systematic and evolutionary microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Stephany Flores RamosThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.ORCID 0000-0002-1918-9769
Silvio D BruggerThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.ORCID 0000-0001-9492-9088
Isabel Fernandez EscapaThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.ORCID 0000-0002-1454-7205
Chelsey A SkeeteThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.
Sean L CottonThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.
Sara M EslamiThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.
Wei GaoThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.
Lindsey BomarThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.
Tommy H TranAlkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicinegrid.39382.33, Houston, Texas, USA.
Dakota S JonesVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Centergrid.270240.3, Seattle, Washington, USA.
Samuel MinotVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Centergrid.270240.3, Seattle, Washington, USA.
Richard J RobertsNew England Biolabsgrid.273406.4, Ipswich, Massachusetts, USA.
Christopher D JohnstonThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.ORCID 0000-0002-6765-2383
Katherine P LemonThe Forsyth Institute (Microbiology), Cambridge, Massachusetts, USA.ORCID 0000-0003-1542-1679
Boston University · USHarvard University · USFred Hutch Cancer Center · USUniversity of Illinois Urbana-Champaign · US

Funding

The SyngenicDNA and μPOET Platform: Overcoming Innate Barriers to Genetic Engineering in Bacteria.R01DE027850 · NIDCR · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JOHNSTON, CHRISTOPHER D · 2017 to 2021
$4.9M
Impact of Commensal Corynebacterium Species on Pathogen Colonization and Microbiota CompositionR01GM117174 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI LEMON, KATHERINE PAIGE · 2016 to 2019
$1.5M
NIDCR NIH HHS R01 DE027850NIGMS NIH HHS R01 GM117174Novartis Stiftung für Medizinisch-Biologische Forschung (Novartis Foundation for Medical-Biological Research) 16B065Promedica Stiftung 1449/MSwiss National Science Foundation and Swiss Foundation for Grants in Biology and Medicine P3SMP3_155315The Forsyth Institute Stimulus Pilot Grant
6 · The paper itself

Abstract

Dolosigranulum pigrum is positively associated with indicators of health in multiple epidemiological studies of human nasal microbiota. Knowledge of the basic biology of

Indexed as

CRISPRDolosigranulum pigrummethylomemobile genetic elementsnasal microbiotapangenomerestriction modification

Identifiers

PMID34546072
PMCPMC8547433
OpenAlexW3199607495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.