Evidence map›Paper›PMID 34545984›Full record

SynthesisPsycho-oncology2022

Are mind-body therapies effective for relieving cancer-related pain in adults? A systematic review and meta-analysis.

Nadia Danon, Muaamar Al-Gobari, Bernard Burnand, Pierre-Yves Rodondi

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Cancer pain.Nature reviews. Disease primers · 2026
    Review
  7. Non-pharmacological interventions for informal cancer caregivers: a JBI scoping review and gap analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Is there a role for hypnosis in palliative care?Palliative care and social practice · 2025
    Review
  15. Article
  16. Review
  17. Immersive virtual reality and neurofeedback for the management of cancer symptoms during treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nadia DanonPain Center and Center for Integrative and Complementary Medicine, Department of Anesthesiology, Lausanne University Hospital and Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-2616-2086
Muaamar Al-GobariCenter for Primary Care and Public Health (Unisanté) and Cochrane Switzerland, University of Lausanne, Lausanne, Switzerland.
Bernard BurnandCenter for Primary Care and Public Health (Unisanté) and Cochrane Switzerland, University of Lausanne, Lausanne, Switzerland.
Pierre-Yves RodondiCenter for Primary Care and Public Health (Unisanté) and Cochrane Switzerland, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-2007-2995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess whether mind-body therapies are effective for relieving cancer-related pain in adults, since at least one-third of adults with cancer are affected by moderate or severe pain.

methodsWe searched for all randomized or quasi-randomized controlled trials that included adults (≥18 years) with cancer-related pain who were treated with mind-body therapies (mindfulness, hypnosis, yoga, guided imagery, and progressive muscle relaxation) in MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), Science Citation Index, Web of Science, trials registers, and reference lists. The primary outcome was pain intensity. We calculated the standardized mean differences and 95% confidence intervals (CIs) and assessed the risk of bias.

resultsWe identified 40 primary studies involving a total of 3569 participants. The meta-analysis included 24 studies (2404 participants) and showed a significant effect of -0.39 (95% CI -0.62 to -0.16) with considerable heterogeneity (I

conclusionsMind-body therapies may be effective in improving cancer pain, but the quality of the evidence is low. There is a need for further high-quality clinical trials.

Indexed as

Cancer PainHypnosisMeditationMindfulnessNeoplasmsYogaAdultHumansadultscancermind-body therapiesoncologypainPsycho-Oncology

Identifiers

PMID34545984
PMCPMC9291932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.