Evidence map›Paper›PMID 34545983›Full record

ReviewAngewandte Chemie (International ed. in English)2021

Repurposing an Antiviral Drug against SARS-CoV-2 Main Protease.

Arighna Sarkar, Kalyaneswar Mandal

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Acta pharmaceutica Sinica. B · 2024
    Review
  5. Development of Masitinib Derivatives with Enhanced MMolecules (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Synthesis,Journal of molecular structure · 2022
    Article
  10. Article
  11. Fullerenes against COVID-19: Repurposing CMolecules (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Repurposing an Antiviral Drug against SARS-CoV-2 Main Protease.Angewandte Chemie (International ed. in English) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arighna SarkarTIFR Centre for Interdisciplinary Sciences, Tata Institute of Fundamental Research Hyderabad, 36/p Gopanpally, Hyderabad, Telangana, 500046, India.
Kalyaneswar MandalTIFR Centre for Interdisciplinary Sciences, Tata Institute of Fundamental Research Hyderabad, 36/p Gopanpally, Hyderabad, Telangana, 500046, India.ORCID 0000-0002-3194-1378

Funding

Department of Atomic Energy, Government of India RTI4007
6 · The paper itself

Abstract

This article highlights recent pioneering work by Günther et al. towards the discovery of potential repurposed antiviral compounds (peptidomimetic and non-peptidic) against the SARS-CoV-2 main protease (M

Indexed as

Drug RepositioningAllosteric SiteAnimalsAntiviral AgentsChlorocebus aethiopsCoronavirus 3C ProteasesCrystallography, X-RayMolecular StructureProtease InhibitorsSARS-CoV-2Vero Cells3C-like proteinase, SARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesProtease Inhibitorsallosteric inhibitorsantiviral drugsdrug screeningSARS-CoV-2X-ray crystallographic screening

Identifiers

PMID34545983
PMCPMC8652770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.