ArticleThe journal of nutrition, health & aging2021
Association of Frailty Status with Risk of Fall among Middle-Aged and Older Adults in China: A Nationally Representative Cohort Study.
Article in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Claims-based frailty index and risk of hospitalisation for hip fracture among adults aged 60-74 years in Tokyo, Japan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- A network analysis of postoperative frailty in older adults: a prospective multicenter study in China.BMC geriatrics · 2026Observational
- The Impact of Falls on Depressive Symptoms in Middle-Aged and Older Chinese Adults: Mediating Effects of Pain.Psychology research and behavior management · 2026Article
- Associations between dimensions of physical activity (intensity, frequency, duration, and volume) and frailty among middle-aged and older Chinese adults.Journal of exercise science and fitness · 2025Article
- Outpatient pooling policy and healthcare satisfaction among middle-aged and older adults: evidence from China.BMC health services research · 2025Article
- Adverse Childhood Experiences and Social Participation on Frailty State Transitions among middle-aged and older adults: evidence from a 10-year prospective study in China.The journal of nutrition, health & aging · 2024Article
- Association of cooking oil and incident of frailty in older adults: a cohort study.BMC geriatrics · 2024Article
- Cultural adaptation and validation of the Sinhala version of the Frail Non-disabled tool (FiND).BMC geriatrics · 2024Article
- Plant-Based Diet Indices and Their Association with Frailty in Older Adults: A CLHLS-Based Cohort Study.Nutrients · 2023Article
- Frailty among middle-aged and older women and men in India: findings from wave 1 of the longitudinal Ageing study in India.BMJ open · 2023Article
- How Neighborhood Structural and Individual Characteristics Affect Frailty Progression: Evidence from the China Health and Retirement Longitudinal Study.The journal of nutrition, health & aging · 2023Article
- The path to healthy ageing in China: a Peking University-Lancet Commission.Lancet (London, England) · 2022Review
- The Incidence of Falls and Related Factors among Chinese Elderly Community Residents in Six Provinces.International journal of environmental research and public health · 2022Article
- Association Between Sensory Loss and Falls Among Middle-Aged and Older Chinese Population: Cross-Sectional and Longitudinal Analyses.Frontiers in medicine · 2021Article
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the association between frailty status and risk of fall among middle-aged and older Chinese people.
designA nationally representative prospective cohort study. SETTING AND
participantsThe study included 13,877 community-dwelling participants aged 45 years and above from the China Health and Retirement Longitudinal Study.
methodsFrailty status was identified by the frailty index of health deficit accumulation. 34 variables at baseline were selected to calculate the frailty index. We excluded participants with incomplete information in construction of the frailty index at baseline. Falls were measured based on the respondents' self-report. We used a logistic regression model to estimate the associations between the frailty status and risk of fall, and subgroup analyses and sensitivity analyses were further conducted.
resultsOf 13,877 participants, 2310 (16.6%) had falls during the observation period. 9027 (65.0%) participants were classified as robust, 4019 (29.0%) participants were classified as pre-frail, and 831 (6.0%) participants were classified as frail. Our results indicated per 0.01 increment in the frailty index was significantly associated with an increased risk of fall among middle-aged and older participants (OR: 1.52, 95%CI: 1.45-1.60). Such association was stronger when frailty was presented as a categorical variable, with an OR of 1.75 (95%CI: 1.59-1.93) for pre-frail and 3.04 (95%CI: 2.60-3.56) for frail. The area under the curve of the logistic model was 0.612 (95%CI: 0.600-0.625). Each 0.01 increment of the frailty index was association with a higher risk of fall among middle-aged (45-59years) participants (OR: 1.44, 95%CI: 1.29-1.60) than among older (≥60 years) participants (OR: 1.28, 95%CI: 1.16-1.41) at baseline (p=0.015 for interaction).
conclusionFrailty was significantly associated with an increased risk of fall among community-dwelling middle-aged and older people in China. It is necessary to screen and recognize frailty status to prevent falls among middle-aged and older adults.
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